An Immune Memory and Negative Selection to Visualize Clinical Pathways from Electronic Health Record Data

2020 ◽  
pp. 99-118
Author(s):  
Mouna Berquedich ◽  
Oulaid Kamach ◽  
Malek Masmoudi ◽  
Laurent Deshayes
Keyword(s):  
Electronic Health Record ◽  
Negative Selection ◽  
Clinical Pathways ◽  
Immune Memory ◽  
Health Record ◽  
Electronic Health Record Data ◽  
Record Data ◽  
Electronic Health

scholarly journals An immune memory and negative selection to visualizing clinical pathways from electronic health record data

2020 ◽  
Vol 19 (1) ◽  
pp. 336
Author(s):  
Mouna Berquedich ◽  
Oulaid Kamach ◽  
Malek Masmoudi ◽  
Laurent Deshayes
Keyword(s):  
Electronic Health Record ◽  
Clinical Pathways ◽  
Immune Memory ◽  
Health Record ◽  
Electronic Health Record Data ◽  
Specific Analysis ◽  
Record Data ◽  
Electronic Health ◽  
Structuring Knowledge ◽  
Treatment Order

Clinical pathways indicate the applicable treatment order of interventions. In this paper we propose a data-driven methodology to extract common clinical pathways from patient-centric Electronic Health Record data (EHR). The analysis of  patient's, can lead to better regarding pathologies. The proposed algorithmic methodology consist to designing a system of control and analysis of patient records based on an analogy between the elements of the new EHRs and the biological immune systems. The detection of patient profiles ensured by biclustering Matrix. We rely on biological immunity to develop a set of models for structuring knowledge extracted from EHR and to make pathway analysis decisions. A specific analysis of the functional data leds to the detection of several types of patients who share the same EHR information. This methodology demonstrates its ability to simultaneously processing data, and is able to providing information for understanding and identifying the path of patients as well as predicting the path of future patients.

scholarly journals An immune memory and negative selection to visualizing clinical pathways from electronic health record data

2020 ◽  
Vol 9 (1) ◽  
pp. 43
Author(s):  
Mouna Berquedich ◽  
Oulaid Kamach ◽  
Malek Masmoudi ◽  
Laurent Deshayes
Keyword(s):  
Electronic Health Record ◽  
Clinical Pathways ◽  
Immune Memory ◽  
Health Record ◽  
Electronic Health Record Data ◽  
Specific Analysis ◽  
Record Data ◽  
Electronic Health ◽  
Structuring Knowledge ◽  
Treatment Order

<p><span>Clinical pathways indicate the applicable treatment order of interventions. In this paper we propose a data-driven methodology to extract common clinical pathways from patient-centric Electronic Health Record data (EHR). The analysis of patient's, can lead to better regarding pathologies. The proposed algorithmic methodology consists to designing a system of control and analysis of patient records based on an analogy between the elements of the new EHRs and the biological immune systems. The detection of patient profiles ensured by biclustering Matrix. We rely on biological immunity to develop a set of models for structuring knowledge extracted from EHR and to make pathway analysis decisions. A specific analysis of the functional data leds to the detection of several types of patients who share the same EHR information. This methodology demonstrates its ability to simultaneously processing data, and is able to providing information for understanding and identifying the path of patients as well as predicting the path of future patients.</span></p>

Automated chronic disease surveillance and visualization using electronic health record data

2011 ◽  
Vol 4 (0) ◽  
Author(s):  
Michael Klompas ◽  
Chaim Kirby ◽  
Jason McVetta ◽  
Paul Oppedisano ◽  
John Brownstein ◽  
...  
Keyword(s):  
Chronic Disease ◽  
Electronic Health Record ◽  
Disease Surveillance ◽  
Health Record ◽  
Electronic Health Record Data ◽  
Record Data ◽  
Electronic Health

Leveraging electronic health record data to inform hospital resource management

2021 ◽  
Author(s):  
José Carlos Ferrão ◽  
Mónica Duarte Oliveira ◽  
Daniel Gartner ◽  
Filipe Janela ◽  
Henrique M. G. Martins
Keyword(s):  
Resource Management ◽  
Electronic Health Record ◽  
Health Record ◽  
Hospital Resource ◽  
Electronic Health Record Data ◽  
Record Data ◽  
Electronic Health

scholarly journals HAI-Proactive: Development of an Automated Surveillance System for Healthcare-Associated Infections in Sweden

2020 ◽  
Vol 41 (S1) ◽  
pp. s39-s39
Author(s):  
Pontus Naucler ◽  
Suzanne D. van der Werff ◽  
John Valik ◽  
Logan Ward ◽  
Anders Ternhag ◽  
...  
Keyword(s):  
Positive Predictive Value ◽  
Electronic Health Record ◽  
Predictive Value ◽  
Surveillance System ◽  
Free Text ◽  
Health Record ◽  
Electronic Health Record Data ◽  
Record Data ◽  
Electronic Health ◽  
Healthcare Associated

Background: Healthcare-associated infection (HAI) surveillance is essential for most infection prevention programs and continuous epidemiological data can be used to inform healthcare personal, allocate resources, and evaluate interventions to prevent HAIs. Many HAI surveillance systems today are based on time-consuming and resource-intensive manual reviews of patient records. The objective of HAI-proactive, a Swedish triple-helix innovation project, is to develop and implement a fully automated HAI surveillance system based on electronic health record data. Furthermore, the project aims to develop machine-learning–based screening algorithms for early prediction of HAI at the individual patient level. Methods: The project is performed with support from Sweden’s Innovation Agency in collaboration among academic, health, and industry partners. Development of rule-based and machine-learning algorithms is performed within a research database, which consists of all electronic health record data from patients admitted to the Karolinska University Hospital. Natural language processing is used for processing free-text medical notes. To validate algorithm performance, manual annotation was performed based on international HAI definitions from the European Center for Disease Prevention and Control, Centers for Disease Control and Prevention, and Sepsis-3 criteria. Currently, the project is building a platform for real-time data access to implement the algorithms within Region Stockholm. Results: The project has developed a rule-based surveillance algorithm for sepsis that continuously monitors patients admitted to the hospital, with a sensitivity of 0.89 (95% CI, 0.85–0.93), a specificity of 0.99 (0.98–0.99), a positive predictive value of 0.88 (0.83–0.93), and a negative predictive value of 0.99 (0.98–0.99). The healthcare-associated urinary tract infection surveillance algorithm, which is based on free-text analysis and negations to define symptoms, had a sensitivity of 0.73 (0.66–0.80) and a positive predictive value of 0.68 (0.61–0.75). The sensitivity and positive predictive value of an algorithm based on significant bacterial growth in urine culture only was 0.99 (0.97–1.00) and 0.39 (0.34–0.44), respectively. The surveillance system detected differences in incidences between hospital wards and over time. Development of surveillance algorithms for pneumonia, catheter-related infections and Clostridioides difficile infections, as well as machine-learning–based models for early prediction, is ongoing. We intend to present results from all algorithms. Conclusions: With access to electronic health record data, we have shown that it is feasible to develop a fully automated HAI surveillance system based on algorithms using both structured data and free text for the main healthcare-associated infections.Funding: Sweden’s Innovation Agency and Stockholm County CouncilDisclosures: None

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