scholarly journals Automated 3D Segmentation of Multiple Surfaces with a Shared Hole: Segmentation of the Neural Canal Opening in SD-OCT Volumes

2014 ◽  
pp. 739-746 ◽  
Author(s):  
Bhavna J. Antony ◽  
Mohammed S. Miri ◽  
Michael D. Abràmoff ◽  
Young H. Kwon ◽  
Mona K. Garvin
Keyword(s):  
3D Segmentation ◽  
Neural Canal ◽  
Sd Oct

scholarly journals Automated 3D Segmentation of Intraretinal Surfaces in SD-OCT Volumes in Normal and Diabetic Mice

2014 ◽  
Vol 3 (5) ◽  
pp. 8 ◽  
Author(s):  
Bhavna J. Antony ◽  
Woojin Jeong ◽  
Michael D. Abràmoff ◽  
Joseph Vance ◽  
Elliott H. Sohn ◽  
...  
Keyword(s):  
Diabetic Mice ◽  
3D Segmentation ◽  
Sd Oct

scholarly journals Effects of myopia and glaucoma in the prelaminar neural canal and anterior lamina cribrosa using 1060-nm swept-source OCT

2021 ◽  
Author(s):  
Sieun Lee ◽  
Morgan Heisler ◽  
Dhanashree Ratra ◽  
Vineet Ratra ◽  
Paul J Mackenzie ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Field ◽  
Optic Disc ◽  
Open Angle Glaucoma ◽  
Lamina Cribrosa ◽  
Optical Coherence ◽  
Inclusion Criteria ◽  
Swept Source ◽  
Neural Canal ◽  
Sd Oct

Purpose: Investigate the effects of myopia and glaucoma in the prelaminar neural canal and anterior lamina cribrosa using 1060-nm swept-source optical coherence tomography Design: Retrospective, cross-sectional study Methods: - Setting: Clinical practice - Patient or study population: 19 controls (38 eyes); 38 glaucomatous subjects (63 eyes). Inclusion criteria for glaucomatous subjects: i) optic disc neural rim loss; ii) peripapillary nerve fibre layer (NFL) loss on spectral domain optical coherence tomography (SD-OCT); iii) glaucomatous visual field defect with an abnormal pattern standard deviation (P<.05); iv) stable SD-OCT, visual field, and optic disc clinical examination for 6 or more months. Inclusion criteria for control subjects: no evidence of retinal or optic nerve pathology. Exclusion criteria: i) retinal diseases or optic neuropathy other than primary open-angle glaucoma; ii) intraocular pressure ≤ 10 mmHg or ≥ 20 mmHg; iii) ocular media opacities; iv) any surgery-related complication deemed inappropriate for the study. - Intervention or observation procedures: Swept-source optical coherence tomography - Main Outcome Measure(s): Bruchs membrane opening (BMO) and anterior laminar insertion (ALI) dimension, prelaminar neural canal dimension, anterior lamina cribrosa surface (ALCS) depth Results: Glaucomatous eyes had more bowed and nasally rotated BMO and ALI, more horizontally skewed prelaminar neural canal, and deeper ALCS than the control eyes. Increased axial length was associated with a wider, longer, and more horizontally skewed neural canal, and decrease in the ALCS depth and curvature. Conclusion: Our findings suggest that glaucomatous posterior bowing or cupping of lamina cribrosa can be significantly confounded by the myopic expansion of the neural canal. This may be related to higher glaucoma risk associated with myopia from decreased compliance and increased susceptibility to IOP-related damage of LC being pulled taut.

scholarly journals Automated segmentation of optic disc in SD-OCT images and cup-to-disc ratios quantification by patch searching-based neural canal opening detection

2015 ◽  
Vol 23 (24) ◽  
pp. 31216 ◽  
Author(s):  
Menglin Wu ◽  
Theodore Leng ◽  
Luis de Sisternes ◽  
Daniel L. Rubin ◽  
Qiang Chen
Keyword(s):  
Optic Disc ◽  
Automated Segmentation ◽  
Neural Canal ◽  
Sd Oct

scholarly journals A machine-learning graph-based approach for 3D segmentation of Bruch’s membrane opening from glaucomatous SD-OCT volumes

2017 ◽  
Vol 39 ◽  
pp. 206-217 ◽  
Author(s):  
Mohammad Saleh Miri ◽  
Michael D. Abràmoff ◽  
Young H. Kwon ◽  
Milan Sonka ◽  
Mona K. Garvin
Keyword(s):  
Machine Learning ◽  
3D Segmentation ◽  
Bruch's Membrane ◽  
Bruch’S Membrane ◽  
Bruch’S Membrane Opening ◽  
Sd Oct

Misalignment of foveal pit and foveal bulge determined by ultrahigh-resolution SD-OCT in normal eyes

2020 ◽  
Vol 258 (10) ◽  
pp. 2131-2139
Author(s):  
Yoshitsugu Matsui ◽  
Ryohei Miyata ◽  
Eriko Uchiyama ◽  
Hisashi Matsubara ◽  
Mineo Kondo
Keyword(s):  
Ultrahigh Resolution ◽  
Sd Oct

scholarly journals Optimization of spectral-domain optical coherence tomography with a supercontinuum source for in vivo motion detection of low reflective outer hair cells in guinea pig cochleae

2021 ◽  
Author(s):  
Fumiaki Nin ◽  
Samuel Choi ◽  
Takeru Ota ◽  
Zhang Qi ◽  
Hiroshi Hibino
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Guinea Pig ◽  
Hair Cells ◽  
Sensory Epithelium ◽  
Outer Hair Cells ◽  
Acquisition Time ◽  
Total Acquisition Time ◽  
Sd Oct

AbstractSound evokes sub-nanoscale vibration within the sensory epithelium. The epithelium contains not only immotile cells but also contractile outer hair cells (OHCs) that actively shrink and elongate synchronously with the sound. However, the in vivo motion of OHCs has remained undetermined. The aim of this work is to perform high-resolution and -accuracy vibrometry in live guinea pigs with an SC-introduced spectral-domain optical coherence tomography system (SD-OCT). In this study, to reveal the effective contribution of SC source in the recording of the low reflective materials with the short total acquisition time, we compare the performances of the SC-introduced SD-OCT (SCSD-OCT) to that of the conventional SD-OCT. As inanimate comparison objects, we record a mirror, a piezo actuator, and glass windows. For the measurements in biological materials, we use in/ex vivo guinea pig cochleae. Our study achieved the optimization of a SD-OCT system for high-resolution in vivo vibrometry in the cochlear sensory epithelium, termed the organ of Corti, in mammalian cochlea. By introducing a supercontinuum (SC) light source and reducing the total acquisition time, we improve the axial resolution and overcome the difficulty in recording the low reflective material in the presence of biological noise. The high power of the SC source enables the system to achieve a spatial resolution of 1.72 ± 0.00 μm on a mirror and reducing the total acquisition time contributes to the high spatial accuracy of sub-nanoscale vibrometry. Our findings reveal the vibrations at the apical/basal region of OHCs and the extracellular matrix, basilar membrane.

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