scholarly journals A New 3-D Automated Computational Method to Evaluate In-Stent Neointimal Hyperplasia in In-Vivo Intravascular Optical Coherence Tomography Pullbacks

2009 ◽  
pp. 776-785 ◽  
Author(s):  
Serhan Gurmeric ◽  
Gozde Gul Isguder ◽  
Stéphane Carlier ◽  
Gozde Unal
Keyword(s):  
Optical Coherence Tomography ◽  
Neointimal Hyperplasia ◽  
Computational Method ◽  
Optical Coherence ◽  
Intravascular Optical Coherence Tomography

Intravascular optical coherence tomography for the evaluation of arterial bifurcations covered by flow diverters

2016 ◽  
Vol 8 (12) ◽  
pp. 1283-1287 ◽  
Author(s):  
Christina Iosif ◽  
Suzana Saleme ◽  
Sebastien Ponsonnard ◽  
Pierre Carles ◽  
Eduardo Pedrolo Silveira ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Side Branch ◽  
Optical Coherence ◽  
Large White ◽  
Sem Images ◽  
In Vivo Evaluation ◽  
Neointimal Thickness ◽  
Intravascular Optical Coherence Tomography

Background and objectiveDue to its high spatial resolution, intravascular optical coherence tomography (OCT) has been used as a valid method for in vivo evaluation of several types of coronary stents at straight lumen and bifurcation sites. We sought to evaluate its effectiveness for flow diverting stents deployed in arterial bifurcation sites involving jailing of a side branch.MethodsFour large white swine were stented with flow diverting stents covering the right common carotid artery–ascending pharyngeal artery bifurcation. After 12 weeks of follow-up the animals were evaluated by digital subtraction angiography and intravascular OCT and subsequently sacrificed. Neointimal thickness on the parent arteries and the free segments of the stent were measured. The stented arteries were harvested and underwent scanning electron microscopy (SEM) imaging. Ostia surface values were measured with OCT three-dimensional (3D) reconstructions and SEM images.ResultsAll endovascular procedures and OCT pullback runs were feasible. Stent apposition was satisfactory on the immediate post-stent OCT reconstructions. At 12-week controls, all stents and jailed branches were patent. Mean neointimal thickness was 0.11±0.04 mm on the free segments of the stent. The mean ostia surface at 12 weeks was 319 750±345 533 μm2 with 3D-OCT reconstructions and 351 198±396 355 μm2 with SEM image-derived calculations. Good correlation was found for ostia surface values between the two techniques; the values did not differ significantly in this preliminary study.ConclusionsIntravascular OCT appears to be a promising technique for immediate and follow-up assessment of the orifice of arterial branches covered by flow diverting stents.

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