Prophylaxe und Therapie von Hämostasestörungen bei Massivtransfusion / Prevention and Therapy in Hemostatic Disorders by Massive Transfusion

Author(s):  
V. Kretschmer ◽  
C. Haas ◽  
M. Weippert-Kretschmer
2001 ◽  
Vol 28 (6) ◽  
pp. 350-353
Author(s):  
V. Kretschmer ◽  
C. Haas ◽  
M. Weippert-Kretschmer

Pflege ◽  
2000 ◽  
Vol 13 (5) ◽  
pp. 297-305 ◽  
Author(s):  
Stefan Roales-Welsch ◽  
Antaszek ◽  
Hense ◽  
Pfeiffer ◽  
Freyenhagen ◽  
...  

In dieser Studie zur Qualitätssicherung in der Prophylaxe und Therapie des Dekubitus durch Auflagedruckmessungen bei Probanden auf sechs Weichlagerungs- und fünf Wechseldrucksystemen war die Zielsetzung, eine Ist-Analyse der am Klinikum eingesetzten Antidekubitushilfsmittel durchzuführen. Außerdem galt es herauszufinden, ob die angewandte Methode der pneumatischen Druckmessung mit Probanden auch im Versorgungsalltag verwendbar ist. Können verlässliche und valide Messdaten erwartet werden, wenn man bei betroffenen Patienten Messungen durchführt? Zur Beantwortung dieser Fragen wurden bei 23/19 Probanden, auch in Seitenlage, durch das Platzieren von Messmatten zwischen Körper und unterschiedliche Antidekubitussysteme Messungen durchgeführt. Bei den Weichlagerungssystemen kann an allen Messorten eine signifikante Druckreduzierung (p < 0,05), am Os coccygis eine hochsignifikante Druckreduzierung (p < 0,01) nachgewiesen werden. Bei den Wechseldrucksystemen liegt der Mittelwert der maximalen Druckbelastung über 12 min bei unterschiedlicher Amplitude (75,47 mmHg–5 mmHg) und verschiedener Frequenz (1,5 min–10 min) zwischen 56,39 mmHg und 38,94 mmHg.


1987 ◽  
Vol 57 (01) ◽  
pp. 118-122 ◽  
Author(s):  
C Thomas Kisker

SummaryAnimal models have added significantly to our understanding of adult hemorrhagic and thrombotic diseases. Few models, however, have been developed for studies of the hemostatic disorders in the fetus and newborn. This report reviews the current information on animal models of fetal and neonatal hemostasis. The requirements of a relevant model are addressed and previous studies using fetal and neonatal animal models are reviewed. A recommendation of a single animal for all studies of fetal and neonatal hemostasis is not possible. However, the lamb has been the most frequently studied and appears to provide relevant information regarding normal development and the factors which may adversely influence hemostasis in the fetus and newborn.


1982 ◽  
Vol 48 (03) ◽  
pp. 277-282 ◽  
Author(s):  
I Nathan ◽  
A Dvilansky ◽  
T Yirmiyahu ◽  
M Aharon ◽  
A Livne

SummaryEchis colorata bites cause impairment of platelet aggregation and hemostatic disorders. The mechanism by which the snake venom inhibits platelet aggregation was studied. Upon fractionation, aggregation impairment activity and L-amino acid oxidase activity were similarly separated from the crude venom, unlike other venom enzymes. Preparations of L-amino acid oxidase from E.colorata and from Crotalus adamanteus replaced effectively the crude E.colorata venom in impairment of platelet aggregation. Furthermore, different treatments known to inhibit L-amino acid oxidase reduced in parallel the oxidase activity and the impairment potency of both the venom and the enzyme preparation. H2O2 mimicked characteristically the impairment effects of L-amino acid oxidase and the venom. Catalase completely abolished the impairment effects of the enzyme and the venom. It is concluded that hydrogen peroxide formed by the venom L-amino acid oxidase plays a role in affecting platelet aggregation and thus could contribute to the extended bleeding typical to persons bitten by E.colorata.


2016 ◽  
Vol 6 (2) ◽  
pp. 60 ◽  
Author(s):  
Hwan Tae Lee ◽  
Pil-Whan Park ◽  
Yiel-Hea Seo ◽  
Jeong-Yeal Ahn ◽  
Ja Young Seo ◽  
...  

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