Test Systems for Detection of Mutagenic Activity of Environmental Pollutants

Author(s):  
N. P. Dubinin ◽  
L. M. Kalinina
1973 ◽  
Vol 21 (1) ◽  
pp. 46-47 ◽  
Author(s):  
G. Röhrborn ◽  
A. Herwig ◽  
P. Propping ◽  
W. Buselmaier

1973 ◽  
Vol 21 (1) ◽  
pp. 44-45 ◽  
Author(s):  
P. Propping ◽  
G. Röhrborn ◽  
W. Buselmaier

1980 ◽  
Vol 5 (1) ◽  
pp. 11-17 ◽  
Author(s):  
Whong Wen-Zong ◽  
Norman D. Speciner ◽  
Gordon S. Edwards

2013 ◽  
Vol 19 (No. 3) ◽  
pp. 90-96 ◽  
Author(s):  
P. Šmerák ◽  
I. Bárta ◽  
Z. Polívková ◽  
J. Bártová ◽  
M. Sedmíková

The authors focused on the amplification of data on the mutagenicity of selected trichothecene mycotoxins (T-2 toxin, vomitoxin) and their combination with aflatoxin B<sub>1</sub>,which is known to be a strong mutagen. Mutagenic activity was investigated using the Ames test in a prokaryote model at low doses (close to 0.1 LD<sub>50</sub>). Whereas the individual trichothecene mycotoxins (T-2 toxin, vomitoxin) did not show any mutagenic activity in the test systems mentioned, in combination with AFB<sub>1</sub>, or as a combination of all three mycotoxins, they showed a mutagenic effect significantly greater than AFB<sub>1</sub> alone in the Ames test (in strain TA98 at all concentrations) as well as in the micronucleus test (combination of T-2 toxin with AFB<sub>1</sub>).


1988 ◽  
Vol 40 (2) ◽  
pp. 183-192 ◽  
Author(s):  
Barbara Przybojewska ◽  
Bogusław Barański ◽  
Ewa Spiechowicz ◽  
Krystyna Sitarek

1983 ◽  
Vol 117 (3-4) ◽  
pp. 337-344 ◽  
Author(s):  
Bryan D. Hardin ◽  
Ronald L. Schuler ◽  
Patricia M. McGinnis ◽  
Richard W. Niemeier ◽  
Randall J. Smith

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