The Hippocampal Formation and Related Structures of the Limbic Lobe: Anatomic — Magnetic Resonance Correlation

1988 ◽  
pp. 32-64 ◽  
Author(s):  
T. P. Naidich ◽  
D. L. Daniels ◽  
V. M. Haughton ◽  
A. Williams ◽  
P. Pech ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Hippocampal Formation ◽  
Limbic Lobe

scholarly journals The hippocampal formation participates in novel picture encoding: evidence from functional magnetic resonance imaging.

1996 ◽  
Vol 93 (16) ◽  
pp. 8660-8665 ◽  
Author(s):  
C. E. Stern ◽  
S. Corkin ◽  
R. G. Gonzalez ◽  
A. R. Guimaraes ◽  
J. R. Baker ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Hippocampal Formation ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging

scholarly journals Grey matter abnormalities in trichotillomania: morphometric magnetic resonance imaging study

2008 ◽  
Vol 193 (3) ◽  
pp. 216-221 ◽  
Author(s):  
Samuel R. Chamberlain ◽  
Lara A. Menzies ◽  
Naomi A. Fineberg ◽  
Natalia del Campo ◽  
John Suckling ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
Affect Regulation ◽  
Grey Matter ◽  
Hippocampal Formation ◽  
Imaging Study ◽  
Resonance Imaging ◽  
Whole Brain ◽  
Axis I

BackgroundTrichotillomania (repetitive hair-pulling) is an Axis I psychiatric disorder whose neurobiological basis is incompletely understood. Whole-brain trichotillomania neuroimaging studies are lacking.AimsTo investigate grey and white matter abnormalities over the whole brain in patients with trichotillomania.MethodEighteen patients with DSM–IV trichotillomania and 19 healthy controls undertook structural magnetic resonance imaging after providing written informed consent. Differences in grey and white matter were investigated using computational morphometry.ResultsPatients with trichotillomania showed increased grey matter densities in the left striatum, left amygdalo-hippocampal formation, and multiple (including cingulate, supplementary motor, and frontal) cortical regions bilaterally.ConclusionsTrichotillomania was associated with structural grey matter changes in neural circuitry implicated in habit learning, cognition and affect regulation. These findings inform animal models of the disorder and highlight key regions of interest for future translational research.

scholarly journals Maturation of the hippocampal formation and amygdala in Macaca mulatta: A volumetric magnetic resonance imaging study

Hippocampus ◽  
2009 ◽  
Vol 20 (8) ◽  
pp. 922-935 ◽  
Author(s):  
Christa Payne ◽  
Christopher J. Machado ◽  
Nancy G. Bliwise ◽  
Jocelyne Bachevalier
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Macaca Mulatta ◽  
Hippocampal Formation ◽  
Imaging Study ◽  
Magnetic Resonance Imaging Study ◽  
Resonance Imaging

Proton Magnetic Resonance Spectroscopy (1H MRS) of the Hippocampal Formation in Schizophrenia: A Pilot Study

1994 ◽  
Vol 165 (4) ◽  
pp. 481-485 ◽  
Author(s):  
Henry A. Nasrallah ◽  
Thomas E. Skinner ◽  
Petra Schmalbrock ◽  
Pierre-Marle Robitaille
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Proton Magnetic Resonance ◽  
Proton Magnetic Resonance Spectroscopy ◽  
Hippocampal Formation ◽  
Resonance Spectroscopy ◽  
Temporal Region ◽  
Post Mortem ◽  
Temporal Structures ◽  
The Right

BackgroundRecent post-mortem and magnetic resonance imaging (MRI) studies strongly suggest a decrease in the volume of the hippocampus and other limbic temporal structures in schizophrenia. Therefore, we hypothesised that N-acetyl aspartate (NAA) which is found mainly in neurons and which can be measured by proton magnetic resonance spectroscopy (1H MRS) would be decreased in the limbic temporal region in schizophrenia.MethodConsenting subjects fulfilling DSM-III-R criteria for schizophrenia (n = 11) and matched healthy volunteers (n = 11) who were recruited in a tertiary university referral centre, participated in a 1H MRS brain study. Proton MRS spectra were obtained from a 12 cm3 voxel (2 × 2 × 3 cm) in the right and left hippocampus/amygdala region. A researcher blind to the source of the spectra, measured the NAA intensity in all subjects, which were then statistically compared across the two groups.ResultsNAA intensities were significantly reduced in the right hippocampus/amygdala region of schizophrenic patients (P = 0.038). The difference of the left side did not reach significance at the 95% confidence level.ConclusionsThe findings of decreased NAA in this study suggest that there may be a decrement in neuronal number or tissue volume of the right hippocampal/amygdala region in schizophrenia. Biochemical alterations in the metabolism of NAA in schizophrenia may be an alternative explanation. The findings are consistent with other types of post-mortem and in vivo evidence for hypoplasia of the limbic temporal structures in schizophrenia, postulated to be of neurodevelopmental pathogenesis.

Areal Measures of Healthy Adults’ Hippocampal Formation on Brain Magnetic Resonance Imaging

2012 ◽  
Vol 23 (2) ◽  
pp. 583-585
Author(s):  
Yan Feng ◽  
Yichen Lu ◽  
Jiachun Feng ◽  
Youqiong Li ◽  
Kailiang Cheng ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hippocampal Formation ◽  
Brain Magnetic Resonance Imaging ◽  
Healthy Adults ◽  
Resonance Imaging

Hippocampal formation and related structures of the limbic lobe: anatomic-MR correlation. Part I. Surface features and coronal sections.

Radiology ◽  
1987 ◽  
Vol 162 (3) ◽  
pp. 747-754 ◽  
Author(s):  
T P Naidich ◽  
D L Daniels ◽  
V M Haughton ◽  
A Williams ◽  
K Pojunas ◽  
...  
Keyword(s):  
Hippocampal Formation ◽  
Surface Features ◽  
Limbic Lobe

Coronal Plane Magnetic Resonance Imaging Measurement of Hippocampal Formation Volume of Healthy Chinese Adults

2017 ◽  
Vol 28 (8) ◽  
pp. 2165-2167
Author(s):  
Hua Zhong ◽  
Ming Yang ◽  
Kai Liang Cheng ◽  
Qiang Fu ◽  
Yong Tian ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hippocampal Formation ◽  
Coronal Plane ◽  
Resonance Imaging ◽  
Chinese Adults ◽  
Magnetic Resonance Imaging Measurement ◽  
Healthy Chinese

scholarly journals The role of the pre-commissural fornix in episodic autobiographical memory and simulation

2019 ◽  
Author(s):  
Angharad N. Williams ◽  
Samuel Ridgeway ◽  
Mark Postans ◽  
Kim S. Graham ◽  
Andrew D. Lawrence ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hippocampal Formation ◽  
Structural Connectivity ◽  
Resonance Imaging ◽  
Construction Of Self ◽  
Future Events ◽  
Magnetic Resonance Imaging Mri ◽  
Future Narratives

AbstractNeuropsychological and functional magnetic resonance imaging (MRI) evidence suggests that the ability to vividly remember our personal past, and imagine future scenarios, involves two closely connected regions: the hippocampus and ventromedial prefrontal cortex (vmPFC). Despite evidence of a direct anatomical connection from hippocampus to vmPFC, it is unknown whether hippocampal-vmPFC structural connectivity supports both past and future-oriented episodic thinking. To address this, we applied diffusion-weighted magnetic resonance imaging (dMRI) and a novel deterministic tractography protocol to reconstruct distinct subdivisions of the fornix previously detected in axonal tracer studies, namely pre-commissural (connecting the hippocampus to vmPFC) and post-commissural (linking the hippocampus and medial diencephalon) fornix, in a group of healthy young adult humans who undertook an adapted past-future autobiographical interview. As predicted, we found that inter-individual differences in pre-commissural - but not post-commissural - fornix microstructure (fractional anisotropy) was significantly correlated with the episodic richness of both past and future autobiographical narratives. Notably, these results remained significant when controlling for both non-episodic narrative content and grey matter volumes of the hippocampus and vmPFC. This study provides novel evidence that reconstructing events from one’s personal past, and constructing possible future events, involves a distinct, structurally-instantiated hippocampal-vmPFC pathway.Significance StatementA novel anatomically-guided protocol that allows the pre-commissural and post-commissural fornix fibers to be separately reconstructed in vivo (Christiansen et al., 2016) was applied to reconstruct the pre-commissural subdivision of the white matter fornix tract (anatomically linking the hippocampal formation to the vmPFC) and investigate its contribution to episodic memory and future simulation. We demonstrated that the amount of episodic details contained in past and future narratives, collected via an adapted autobiographical interview, was positively correlated with pre-, but not post-, commissural fornix microstructure. These findings highlight how inter-individual variation in the pre-commissural subdivision of the fornix underpins the construction of self-reflective, contextual events – for both the past and future.

Sign in / Sign up

Export Citation Format

Share Document