Assessment of Cerebral Autoregulation from Respiratory Oscillations in Ventilated Patients After Traumatic Brain Injury

Author(s):  
Philip M. Lewis ◽  
Peter Smielewski ◽  
Jeffrey V. Rosenfeld ◽  
John D. Pickard ◽  
Marek Czosnyka
2018 ◽  
Author(s):  
Ryan Martin ◽  
Lara Zimmermann ◽  
Marike Zwienenberg ◽  
Kee D Kim ◽  
Kiarash Shahlaie

The management of traumatic brain injury focuses on the prevention of second insults, which most often occur because of a supply/demand mismatch of the cerebral metabolism. The healthy brain has mechanisms of autoregulation to match the cerebral blood flow to the cerebral metabolic demand. After trauma, these mechanisms are disrupted, leaving the patient susceptible to episodes of hypotension, hypoxemia, and elevated intracranial pressure. Understanding the normal and pathologic states of the cerebral blood flow is critical for understanding the treatment choices for a patient with traumatic brain injury. In this chapter, we discuss the underlying physiologic principles that govern our approach to the treatment of traumatic brain injury. This review contains 3 figures, 1 table and 12 references Key Words: cerebral autoregulation, cerebral blood flow, cerebral metabolic rate, intracranial pressure, ischemia, reactivity, vasoconstriction, vasodilation, viscosity


Brain Injury ◽  
2017 ◽  
Vol 32 (2) ◽  
pp. 269-275 ◽  
Author(s):  
Monica S Vavilala ◽  
Carly K Farr ◽  
Arraya Watanitanon ◽  
BS Crystalyn Clark-Bell ◽  
Theerada Chandee ◽  
...  

2010 ◽  
Vol 14 (2) ◽  
pp. 188-193 ◽  
Author(s):  
Enrico Sorrentino ◽  
Karol P. Budohoski ◽  
Magdalena Kasprowicz ◽  
Peter Smielewski ◽  
Basil Matta ◽  
...  

2006 ◽  
Vol 28 (4-5) ◽  
pp. 348-353 ◽  
Author(s):  
M.S. Vavilala ◽  
S. Muangman ◽  
Nuj Tontisirin ◽  
D. Fisk ◽  
C. Roscigno ◽  
...  

2010 ◽  
Vol 3 (1) ◽  
pp. 6-9
Author(s):  
Gill E. Sviri ◽  
David W. Newel

Sign in / Sign up

Export Citation Format

Share Document