Clinical Trials in Pediatric Brain Tumors; Radiotherapy

2012 ◽  
pp. 183-197 ◽  
Author(s):  
Anna Skowronska-Gardas ◽  
Marzanna Chojnacka ◽  
Katarzyna Pedziwiatr
Keyword(s):  
Clinical Trials ◽  
Brain Tumors ◽  
Pediatric Brain Tumors ◽  
Pediatric Brain

scholarly journals Immunotherapy for pediatric brain tumors: past and present

2019 ◽  
Vol 21 (10) ◽  
pp. 1226-1238 ◽  
Author(s):  
Jessica B Foster ◽  
Peter J Madsen ◽  
Meenakshi Hegde ◽  
Nabil Ahmed ◽  
Kristina A Cole ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Brain Tumors ◽  
Pediatric Brain Tumors ◽  
Adoptive T Cell Therapy ◽  
Active Immunotherapy ◽  
T Cell Therapy ◽  
The Past ◽  
Formidable Challenge ◽  
Recent Developments ◽  
Pediatric Brain

AbstractThe field of cancer immunotherapy has progressed at an accelerated rate over the past decade. Pediatric brain tumors thus far have presented a formidable challenge for immunotherapy development, given their typically low mutational burden, location behind the blood–brain barrier in a unique tumor microenvironment, and intratumoral heterogeneity. Despite these challenges, recent developments in the field have resulted in exciting preclinical evidence for various immunotherapies and multiple clinical trials. This work reviews the history and advances in active immunotherapy, checkpoint blockade, and adoptive T-cell therapy for pediatric brain tumors, including ongoing clinical trials.

scholarly journals Clinical trials using molecular stratification of pediatric brain tumors

2020 ◽  
Vol 9 (2) ◽  
pp. 144-156
Author(s):  
Samuel Z. Hanz ◽  
Oluwaseyi Adeuyan ◽  
Grace Lieberman ◽  
Tammy Hennika
Keyword(s):  
Clinical Trials ◽  
Brain Tumors ◽  
Pediatric Brain Tumors ◽  
Molecular Stratification ◽  
Pediatric Brain
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