Rational Design of a New Class of DNA Cleaver Based on Prediction of Minor Groove Binding Interactions and NMR Structural Studies

1996 ◽  
pp. 177-193
Author(s):  
Amanda Wilton ◽  
Seyed Sadat-Ebrahimi ◽  
John A. Parkinson ◽  
Julie Andrews ◽  
Kenneth T. Douglas
Keyword(s):  
Rational Design ◽  
Minor Groove ◽  
Minor Groove Binding ◽  
Structural Studies ◽  
Groove Binding ◽  
Binding Interactions ◽  
New Class

A New Class of Symmetric Bisbenzimidazole-Based DNA Minor Groove-Binding Agents Showing Antitumor Activity

2001 ◽  
Vol 44 (2) ◽  
pp. 138-144 ◽  
Author(s):  
John Mann ◽  
Anne Baron ◽  
Yaw Opoku-Boahen ◽  
Eric Johansson ◽  
Gary Parkinson ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Minor Groove ◽  
Minor Groove Binding ◽  
Groove Binding ◽  
Dna Minor Groove ◽  
New Class ◽  
Binding Agents

FTIR Study of Specific Binding Interactions Between DNA Minor Groove Binding Ligands and Polynucleotides

1992 ◽  
Vol 10 (3) ◽  
pp. 565-575 ◽  
Author(s):  
F. Adnet ◽  
J. Liquier ◽  
E. Taillandier ◽  
Malvinder P. Singh ◽  
K. Ekambareswara Rao ◽  
...  
Keyword(s):  
Specific Binding ◽  
Minor Groove ◽  
Minor Groove Binding ◽  
Groove Binding ◽  
Binding Interactions ◽  
Dna Minor Groove ◽  
Ftir Study

ChemInform Abstract: A New Class of Symmetric Bisbenzimidazole-Based DNA Minor Groove-Binding Agents Showing Antitumor Activity.

ChemInform ◽  
2001 ◽  
Vol 32 (16) ◽  
pp. no-no
Author(s):  
John Mann ◽  
Anne Baron ◽  
Yaw Opoku-Boahen ◽  
Eric Johannsson ◽  
Gary Parkinson ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Minor Groove ◽  
Minor Groove Binding ◽  
Groove Binding ◽  
Dna Minor Groove ◽  
New Class ◽  
Binding Agents

Rational Design of DNA Minor Groove-Binding Anti-Tumor Drugs

1987 ◽  
pp. 209-221
Author(s):  
Richard E. Dickerson ◽  
Philip Pjura ◽  
Mary L. Kopka ◽  
David Goodsell ◽  
Chun Yoon
Keyword(s):  
Rational Design ◽  
Minor Groove ◽  
Minor Groove Binding ◽  
Groove Binding ◽  
Dna Minor Groove ◽  
Tumor Drugs
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