Improvement of myocardial perfusion and enhancement of washout during coronary artery occlusion by intermittent pressure controlled coronary sinus occlusions

1985 ◽  
pp. 28-31
Author(s):  
D. Glogar ◽  
W. Mohl ◽  
H. Mayr ◽  
P. Schindler ◽  
F. Kaindl ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Myocardial Perfusion ◽  
Coronary Sinus ◽  
Coronary Artery Occlusion ◽  
Artery Occlusion ◽  
Pressure Controlled

Changes in Hemodynamics and Bradykinin Concentration in Coronary Sinus Blood in Experimental Coronary Artery Occlusion

1977 ◽  
Vol 18 (5) ◽  
pp. 679-689 ◽  
Author(s):  
Keiichi HASHIMOTO ◽  
Masaru HIROSE ◽  
Soichi FURUKAWA ◽  
Hirokazu HAYAKAWA ◽  
Eiichi KIMURA
Keyword(s):  
Coronary Artery ◽  
Coronary Sinus ◽  
Coronary Artery Occlusion ◽  
Artery Occlusion ◽  
Coronary Sinus Blood

Effect of exercise on coronary pressure-flow relationship in hypertrophied left ventricle

1995 ◽  
Vol 269 (1) ◽  
pp. H271-H281 ◽  
Author(s):  
D. J. Duncker ◽  
J. Zhang ◽  
T. J. Pavek ◽  
M. J. Crampton ◽  
R. J. Bache
Keyword(s):  
Coronary Artery ◽  
Myocardial Perfusion ◽  
Diastolic Pressure ◽  
Coronary Artery Occlusion ◽  
Artery Occlusion ◽  
Left Ventricular ◽  
Back Pressure ◽  
Pressure Flow ◽  
Pronounced Increase ◽  
Coronary Pressure

Left ventricular (LV) hypertrophy (LVH) secondary to chronic pressure overload is associated with increased susceptibility to myocardial hypoperfusion and ischemia during exercise. The present study was performed to determine whether exercise causes alterations in minimum coronary resistance or effective back pressure [coronary pressure at zero flow (Pzf)] that limit maximum myocardial perfusion in the hypertrophied heart. Ascending aortic banding in 7 dogs increased the LV weight-to-body weight ratio to 7.7 +/- 0.3 g/kg compared with 4.6 +/- 0.2 g/kg in 11 normal dogs (P < 0.01). Maximum coronary vasodilation was produced by intracoronary infusion of adenosine. Under resting conditions, the slope of the pressure-flow relationship (conductance) was significantly lower in the LVH animals than in the normal dogs (7.2 +/- 0.8 vs. 11.9 +/- 0.8 x 10(-2) ml.min-1.g-1.mmHg-1; P < 0.01); the slope correlated with the degree of hypertrophy r = 0.74; P < 0.001). The Pzf measured during total coronary artery occlusion (Pzf,measured) was significantly elevated in LVH compared with normal dogs (25.6 +/- 2.2 vs. 13.0 +/- 1.2 mmHg; P < 0.01); Pzf,measured was positively correlated (r = 0.78, P < 0.0005) with LV end-diastolic pressure measured during total coronary artery occlusion (9.0 +/- 1.1 mmHg in normal dogs and 22.2 +/- 3.2 mmHg in LVH dogs; P < 0.01). Graded treadmill exercise to maximum heart rates of 210 +/- 9 and 201 +/- 8 beats/min in normal and LVH animals, respectively, caused similar decreases in the slope of the pressure-flow relationship in LVH (from 7.7 +/- 0.9 to 6.1 +/- 0.8 x 10(-2) ml.min-1.g-1.mmHg-1; P < 0.01) and normal dogs (from 11.9 +/- 0.8 to 10.0 +/- 0.7 x 10(-2) ml.min-1.g-1.mmHg-1; P < 0.01). However, exercise-induced increases in Pzf,measured were significantly greater in the LVH animals (from 25.6 +/- 2.2 to 40.8 +/- 2.1 mmHg; P < 0.01) than in normal animals (from 13.0 +/- 1.2 to 24 +/- 2.1 mmHg; P < 0.01) (P < 0.01 LVH vs. normal). The greater increase in Pzf paralleled a more pronounced increase in LV end-diastolic pressure in the LVH dogs from 22.2 +/- 3.2 to 39.1 +/- 2.7 mmHg) than in normal dogs from 9.0 +/- 1.1 to 14.2 +/- 2.0 mmHg). The results suggest that exaggerated increases in filling pressure during exercise in the hypertrophied left ventricles contributed to impairment of myocardial perfusion during exercise by augmenting the back pressure, which opposes coronary flow.(ABSTRACT TRUNCATED AT 400 WORDS)

Magnesium-enriched coronary sinus retroperfusion during acute coronary artery occlusion

2002 ◽  
Vol 13 (6) ◽  
pp. 331-336 ◽  
Author(s):  
S. Fehmi Katrcoğlu ◽  
A. Tulga Ulus ◽  
Zülfikar Sartaş ◽  
Ayşen Aksöyek ◽  
Ufuk Tütün ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Sinus ◽  
Coronary Artery Occlusion ◽  
Artery Occlusion

Localization and Quantification of Myocardium at Risk by Myocardial Perfusion SPECT During Coronary Artery Occlusion

2004 ◽  
Vol 57 (7) ◽  
pp. 635-643
Author(s):  
Osvaldo Pereztol-Valdés ◽  
Jaume Candell-Riera ◽  
Guillermo Oller-Martínez ◽  
Santiago Aguadé-Bruix ◽  
Joan Castell-Conesa ◽  
...  
Keyword(s):  
At Risk ◽  
Coronary Artery ◽  
Myocardial Perfusion ◽  
Coronary Artery Occlusion ◽  
Myocardial Perfusion Spect ◽  
Artery Occlusion ◽  
Perfusion Spect ◽  
Myocardium At Risk

Improved distribution of antegrade cardioplegic solution with simultaneous coronary sinus occlusion following acute coronary artery occlusion

1992 ◽  
Vol 53 (1) ◽  
pp. 98-102 ◽  
Author(s):  
Shu-Ching Sun ◽  
Maurizio Diaco ◽  
Gregory S. Couper ◽  
Paolo Masetti ◽  
Rita G. Laurence ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Sinus ◽  
Coronary Artery Occlusion ◽  
Artery Occlusion ◽  
Cardioplegic Solution

scholarly journals Coronary sinus fow measured by pulsed Doppler ultrasound is a powerful indicator of coronary blood supply – a pig heart in vitro study.

2016 ◽  
Vol 18 (2) ◽  
pp. 190 ◽  
Author(s):  
Xiao-Zhi Zheng ◽  
Jing Wu ◽  
Jie Hua
Keyword(s):  
Coronary Artery ◽  
Doppler Ultrasound ◽  
Blood Supply ◽  
Coronary Sinus ◽  
Coronary Artery Occlusion ◽  
Artery Occlusion ◽  
Pulsed Doppler ◽  
Operating Characteristics ◽  
Pulsed Doppler Ultrasound

Aims: To evaluate the correlation between the coronary sinus fow and the infusion volume in the coronaries and assess the performance of coronary sinus fow in predicting coronary artery occlusion in an isolated pig heart. Material and methods: The coronary sinus fow was measured in 16 isolated pig hearts by pulsed Doppler ultrasound. The correlation between the coronary sinus fow and the infusion volume in different coronary artery was analyzed, and the performance of coronary sinus fow in predicting different coronary artery occlusion was deducted. Results: There were no statistically signifcant differences between the coronary sinus fow and the infusion volume in different coronary artery (p>0.05). The correlations between the coronary sinus fow and the infusion volume in left anterior descending coronary artery (LAD), left circumfex coronary artery (LCX), LAD and LCX, and LAD, LCX and right coronary artery (RCA) were all higher than 0.85 (p<0.01), and those of RCA, LAD and RCA, and LCX and RCA were between 0.6 and 0.8 (p<0.05). The areas under the receiver operating characteristics curve (AUC) were all higher than 0.90 (p<0.05) in predicting any two coronaries occlusion (<50% and 100%) and three coronaries occlusion (<50%) with a >85% sensitivity and specifcity. Excepting RCA mild occlusion (<50%), AUCs in predicting one coronary occlusion (<50% and 100%) were between 0.7 and 0.9, with >80% sensitivity and specifcity. Conclusions: The coronary sinus fow measured by pulsed Doppler ultrasound can effectively and exactly refect the infusion volume in coronaries, which is a powerful indicator of coronary blood supply.

Reduction of the infarcted area with the use of simplified coronary sinus retroperfusion during experimental coronary artery occlusion

2000 ◽  
Vol 73 (2) ◽  
pp. 115-121 ◽  
Author(s):  
S.Fehmi Katircioǧlu ◽  
Perran Gökçe ◽  
A.Tulga Ulus ◽  
Ufuk Tütün ◽  
Nusret Apaydin ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Sinus ◽  
Coronary Artery Occlusion ◽  
Artery Occlusion ◽  
Infarcted Area
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