scholarly journals Visualization of the Pathological Changes After Spinal Cord Injury (-From Bench to Bed Side-)

2019 ◽  
pp. 133-139
Author(s):  
Masaya Nakamura
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Pathological Changes ◽  
Cord Injury

Possible implication of leukocytes in secondary pathological changes after spinal cord injury

Injury ◽  
1997 ◽  
Vol 28 (3) ◽  
pp. 215-217 ◽  
Author(s):  
S. Katoh ◽  
T. Ikata ◽  
M. Tsubo ◽  
Y. Hamada ◽  
W.S. El Masry
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Pathological Changes ◽  
Cord Injury

scholarly journals A progressive compression model of thoracic spinal cord injury in mice: function assessment and pathological changes in spinal cord

2017 ◽  
Vol 12 (8) ◽  
pp. 1365 ◽  
Author(s):  
Zhi-zhong Li ◽  
Guo-dong Sun ◽  
Yan Chen ◽  
Zhi-gang Zhou ◽  
Shu-xian Yang ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Pathological Changes ◽  
Thoracic Spinal Cord ◽  
Compression Model ◽  
Thoracic Spinal ◽  
Cord Injury ◽  
Function Assessment

scholarly journals Pathological changes of distal motor neurons after complete spinal cord injury

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Kazuya Yokota ◽  
Kensuke Kubota ◽  
Kazu Kobayakawa ◽  
Takeyuki Saito ◽  
Masamitsu Hara ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Motor Neurons ◽  
Pathological Changes ◽  
Cord Injury ◽  
Complete Spinal Cord Injury

scholarly journals Histological and Immunohistochemical Effects of Neuroectodermal Cells Transplantation after Spinal Cord Injury in Rats

2018 ◽  
Author(s):  
Saleh Al-Karim ◽  
Wafaa S. Ramadan ◽  
Ghada A. Abdel-Hamid ◽  
Fatma Al Qudsi
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Male Rats ◽  
Osmic Acid ◽  
Pathological Changes ◽  
Histological Changes ◽  
Cord Injury ◽  
Expression Evidence ◽  
Reactive Astrocytosis ◽  
Control Sham

Background: In spinal cord injury, radical treatment is still a persistent hope for patients and clinicians. Our study aimed to determine the different histological changes in central, cranial and caudal sites of compressed spinal cord as a result of neuroectodermal stem cells (NESCs) transplantation in rats. Material and methods: For extraction of NESCs, future brains were extracted from mice embryos (10-days old) and cultured.  Eighty, male rats were divided randomly into control, sham (20 rats each); while 40 rats were subjected to compressed spinal cord injury (CSCI). Seven days after spinal cord injury, rats were subdivided into 2 groups (20 rats each); an untreated and treated with NESCs injected cranial and caudal to the site of the spinal cord injury. Rats were sacrificed 4 weeks after transplantations of NESCs and specimens from the spinal cord at the central, cranial and caudal to site of spinal cord injury were proceeded to be stained with haematoxylin & eosin, osmic acid and Immunohistochemistry of glial fibrillary acidic protein (GFAP). Results: Sections of CSCI revealed areas of hemorrhages, necrosis and cavitation limited by reactive astrocytosis, with upregulation of GFAP expression. Evidence of remyelination and mitigation of histopathological features, reactive astrocytosis in CSCI sections were more pronounced in cranial than in caudal region. Conclusions: NESCs transplantation ameliorated the pathological changes, promoted remyelination.

Pathological changes within two weeks following spinal cord injury in a canine model

2021 ◽  
Author(s):  
Yuya Nakamoto ◽  
Gentarou Tsujimoto ◽  
Akito Ikemoto ◽  
Koichi Omori ◽  
Tatsuo Nakamura
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Canine Model ◽  
Pathological Changes ◽  
Cord Injury
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