In this paper, we propose the modified minsum decoding algorithm of LDPC(Low-Density Parity-Check) code in the simplified difference-domain on the basis of detailed analysis of LDPC decoding algorithm in difference-domain. The simulation indicates that the proposed decoding algorithm offers almost no performance degradation compared with the BP(Belief Propagation) decoding algorithm in log-domain and the decoding algorithm in difference-domain and offers better performance than minsum decoding algorithm in log-domain and greatly reduces the computation complexity in AWGN(Additive White Gaussian Noise) channel and under BPSK(Binary Phase Shift Keying) modulation.