Voltage-dependent K+ channels in the sarcolemma of mouse skeletal muscle

1991 ◽  
Vol 419 (5) ◽  
pp. 486-491 ◽  
Author(s):  
H. Brinkmeier ◽  
E. Zachar ◽  
R. R�del
Keyword(s):  
Skeletal Muscle ◽  
K Channels ◽  
Mouse Skeletal Muscle ◽  
Voltage Dependent

scholarly journals Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2 C12 cells

FEBS Letters ◽  
1992 ◽  
Vol 310 (2) ◽  
pp. 162-166 ◽  
Author(s):  
Florian Lesage ◽  
Bernard Attali ◽  
Michel Lazdunski ◽  
Jacques Barhanin
Keyword(s):  
Skeletal Muscle ◽  
Developmental Expression ◽  
K Channels ◽  
Mouse Skeletal Muscle

Differential Expression of Kv1.3 and Kv1.5 Voltage-Dependent K+Channels in Human Skeletal Muscle Sarcomas

2012 ◽  
Vol 30 (3) ◽  
pp. 203-208 ◽  
Author(s):  
Joanna Bielanska ◽  
Javier Hernández-Losa ◽  
Teresa Moline ◽  
Rosa Somoza ◽  
Santiago Ramón y Cajal ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Differential Expression ◽  
Human Skeletal Muscle ◽  
K Channels ◽  
Voltage Dependent

scholarly journals Activation of ATP-dependent K+ channels by metabolic poisoning in adult mouse skeletal muscle: role of intracellular Mg(2+) and pH.

1995 ◽  
Vol 485 (2) ◽  
pp. 283-296 ◽  
Author(s):  
B Allard ◽  
M Lazdunski ◽  
O Rougier
Keyword(s):  
Skeletal Muscle ◽  
Adult Mouse ◽  
K Channels ◽  
Mouse Skeletal Muscle

scholarly journals Elevated subsarcolemmal Ca2+ in mdx mouse skeletal muscle fibers detected with Ca2+-activated K+ channels

2000 ◽  
Vol 97 (9) ◽  
pp. 4950-4955 ◽  
Author(s):  
N. Mallouk ◽  
V. Jacquemond ◽  
B. Allard
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibers ◽  
Mdx Mouse ◽  
K Channels ◽  
Mouse Skeletal Muscle ◽  
Skeletal Muscle Fibers

Endothelium-dependent Vasodilation in Myogenically Active Mouse Skeletal Muscle Arterioles: Role of EDH and K+Channels

2009 ◽  
Vol 16 (5) ◽  
pp. 377-390 ◽  
Author(s):  
Simon J. Potocnik ◽  
Iain McSherry ◽  
Hong Ding ◽  
Timothy V. Murphy ◽  
Neela Kotecha ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
K Channels ◽  
Mouse Skeletal Muscle

scholarly journals Mobility of voltage-dependent ion channels and lectin receptors in the sarcolemma of frog skeletal muscle.

1986 ◽  
Vol 87 (6) ◽  
pp. 955-983 ◽  
Author(s):  
R E Weiss ◽  
W M Roberts ◽  
W Stühmer ◽  
W Almers
Keyword(s):  
Skeletal Muscle ◽  
Ion Channels ◽  
Delayed Rectifier ◽  
Na Channels ◽  
Frog Skeletal Muscle ◽  
Con A ◽  
Lectin Receptors ◽  
K Channels ◽  
Average Diffusion Coefficient ◽  
Voltage Dependent

The mobility of lectin receptors and of two types of ion channels was studied in skeletal muscles of the frog Rana temporaria. Lectin receptors were labeled with fluorescent derivatives of succinyl-concanavalin A (Con A) or wheat germ agglutinin (WGA), and their mobility was measured by fluorescence recovery after photobleaching. Of the receptors for WGA, approximately 53% were free to diffuse in the plane of the membrane, with an average diffusion coefficient as found in other preparations (D = 6.4 X 10(-11) cm2/s). Con A receptors were not measurably mobile. The mobility of voltage-dependent Na and K (delayed rectifier) channels was investigated with the loose-patch clamp method, coupled with through-the-pipette photodestruction of channels by ultraviolet (UV) light. Na channels were not measurably mobile (D less than or equal to 10(-12) cm2/s). With K channels, photodestruction was followed by a small but consistent recovery of K current, which suggested that some K channels diffused in the plane of the membrane. Our results with K currents are best fit if 25% of the K channels diffuse with D = 5 X 10(-11) cm2/s, with the remainder being immobile. For both Na and K channels, photodestruction by UV was most effective at a wavelength of approximately 289 nm. At this wavelength, the energy density required for an e-fold reduction in the number of functional channels was 0.40 J/cm2 for Na channels and 0.94 J/cm2 for K channels. Irradiation at this wavelength and dose did not measurably diminish the mobility of WGA receptors; hence, the immobility of Na and most K channels is not due to UV irradiation. It is concluded that mobile and immobile membrane proteins coexist in the sarcolemma of frog skeletal muscle, and that voltage-dependent Na and K channels are singled out for immobilization.

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