Electron microscopic study on Wallerian degeneration of the peripheral nerve

1961 ◽  
Vol 54 (1) ◽  
pp. 39-67 ◽  
Author(s):  
Susumu Ohmi
Keyword(s):  
Peripheral Nerve ◽  
Microscopic Study ◽  
Electron Microscopic Study ◽  
Wallerian Degeneration ◽  
Electron Microscopic

scholarly journals Proper microsurgical nerve suture may impede Wallerian degeneration of completely transected nerves: an electron microscopic study

1983 ◽  
Vol 41 (3) ◽  
pp. 215-227 ◽  
Author(s):  
Eros Abrantes Erhart ◽  
Ciro Ferreira da Silva ◽  
Claudio Fava Chagas
Keyword(s):  
Microscopic Study ◽  
Electron Microscopic Study ◽  
Wallerian Degeneration ◽  
Distal Segment ◽  
Electron Microscopic ◽  
Nerve Suture ◽  
Previous Statement ◽  
Microscopic Findings

Electron microscopic findings on the nerve of the biventer cervicis muscle of the chick, which was completely transected and immediately after submitted to an adequate microsurgical nerve suture, confirmed our previous statement that proper microsurgical nerve suture may impede the Wallerian degeneration that normally occurs in the distal segment of a completely transected nerve.

scholarly journals TRANSIENT, FOCAL ACCUMULATION OF AXONAL MITOCHONDRIA DURING THE EARLY STAGES OF WALLERIAN DEGENERATION

1962 ◽  
Vol 12 (2) ◽  
pp. 361-383 ◽  
Author(s):  
Henry deF. Webster
Keyword(s):  
Guinea Pig ◽  
Microscopic Study ◽  
Electron Microscopic Study ◽  
Wallerian Degeneration ◽  
Osmium Tetroxide ◽  
Crush Injury ◽  
Electron Microscopic ◽  
Myelinated Fibers ◽  
Unmyelinated Axons ◽  
Sciatic Nerves

Wallerian degeneration was produced in guinea pig sciatic nerves by a crush injury. At intervals of 2, 12, 24, 36, 48, 72, and 96 hours after the crush, the nerves were fixed in osmium tetroxide, and blocks from the distal, degenerating segment identified topographically prior to embedding in Araldite or Epon. Phase and electron microscopic study of serial cross- and longitudinal sections reveals a striking, localized accumulation of axonal mitochondria which precedes or accompanies the swelling and fragmentation previously reported by others. These focal accumulations of mitochondria are transient and are most frequently observed in the paranodal axoplasm of large myelinated fibers 24 to 36 hours after crush injury, but are also occasionally identified in small myelinated fibers and unmyelinated axons. Migration and proliferation of axonal mitochondria are considered as possible explanations of these observations.

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