Ordered mapping of three alpha satellite DNA subsets on human chromosome 22

1995 ◽  
Vol 3 (2) ◽  
pp. 124-127 ◽  
Author(s):  
Rachele Antonacci ◽  
Mariano Rocchi ◽  
Nicoletta Archidiacono ◽  
Antonio Baldini
1994 ◽  
Vol 20 (5) ◽  
pp. 443-448 ◽  
Author(s):  
Mariano Rocchi ◽  
Nicoletta Archidiacono ◽  
Rachele Antonacci ◽  
Palma Finelli ◽  
Leonardo D'Aiuto ◽  
...  

1990 ◽  
Vol 10 (12) ◽  
pp. 6374-6380 ◽  
Author(s):  
R Wevrick ◽  
W C Earnshaw ◽  
P N Howard-Peebles ◽  
H F Willard

A familial, constitutionally rearranged human chromosome 17 is deleted for much of the DNA in its centromeric region but retains full mitotic centromere activity. Fluorescence in situ hybridization, pulsed-field gel electrophoresis, and Southern blot analysis of the residual centromeric region revealed a approximately 700-kb centromeric array of tandemly repeated alpha satellite DNA that was only approximately 20 to 30% as large as a normal array. This deletion was associated with a reduction in the amount of the centromere-specific antigen CENP-B detected by indirect immunofluorescence. The coincidence of the primary constriction, the small residual array of alpha satellite DNA, and the reduced amount of detectable CENP-B support the hypothesis that CENP-B is associated with alpha satellite DNA. Furthermore, the finding that both the deleted chromosome 17 and its derivative supernumerary fragment retained mitotic function and possess centromeric protein antigens suggests that human centromeres are structurally and functionally repetitive.


1987 ◽  
Vol 77 (2) ◽  
pp. 151-156 ◽  
Author(s):  
John S. Waye ◽  
Gillian M. Greig ◽  
Huntington F. Willard

Genomics ◽  
1988 ◽  
Vol 3 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Peter Devilee ◽  
Tim Kievits ◽  
John S. Waye ◽  
Peter L. Pearson ◽  
Huntington F. Willard

Chromosoma ◽  
1987 ◽  
Vol 95 (3) ◽  
pp. 182-188 ◽  
Author(s):  
John S. Waye ◽  
Leslie A. Creeper ◽  
Huntington F. Willard

Genomics ◽  
1993 ◽  
Vol 18 (2) ◽  
pp. 230-235 ◽  
Author(s):  
L. D'Aiuto ◽  
R. Antonacci ◽  
R. Marzella ◽  
N. Archidiacono ◽  
M. Rocchi

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