DNA synthesis in nuclei and nuclear matrices of regenerating rat liver: Effect of whole-body gamma irradiation

1991 ◽  
Vol 30 (4) ◽  
pp. 267-276 ◽  
Author(s):  
V. P. Dave ◽  
M. S. Patil ◽  
V. N. Pandey ◽  
D. S. Pradhan
Keyword(s):  
Dna Synthesis ◽  
Gamma Irradiation ◽  
Rat Liver ◽  
Whole Body ◽  
Regenerating Rat Liver

DEOXYCYTIDYLATE DEAMINASE LEVELS IN REGENERATING RAT LIVER

1961 ◽  
Vol 39 (6) ◽  
pp. 1043-1054 ◽  
Author(s):  
D. K. Myers ◽  
C. Anne Hemphill ◽  
Constance M. Townsend
Keyword(s):  
Dna Synthesis ◽  
Liver Regeneration ◽  
Partial Hepatectomy ◽  
Rat Liver ◽  
Deoxyribonucleic Acid ◽  
Regenerating Liver ◽  
Regenerating Rat Liver ◽  
High Level ◽  
Early Regeneration

Deoxycytidylate deaminase activity and net synthesis of deoxyribonucleic acid (DNA) in vivo were found to increase at approximately the same time during the early stages of liver regeneration. However, deaminase activity in the regenerating liver remained at a high level for 1 day after DNA synthesis had slowed down again during the later stages of regeneration. The increase in deaminase activity was restricted as a result of exposure to 600 r X radiation during early regeneration, but this effect only became evident 11–16 hours after the irradiation. Irradiation on the second day after partial hepatectomy, when deaminase levels in control regenerating livers were relatively constant, failed to affect the deaminase activity immediately but did produce a 40–50% decrease in activity 11–16 hours later. Other antimitotic agents, e.g., colchicine, had little effect on deaminase activity.

scholarly journals Blunted DNA synthesis and delayed S-phase entry following inhibition of Cdk2 activity in the regenerating rat liver

2005 ◽  
Vol 85 (4) ◽  
pp. 562-571 ◽  
Author(s):  
Peter Stärkel ◽  
Christine De Saeger ◽  
Christine Sempoux ◽  
Eric Legrand ◽  
Isabelle Leclercq ◽  
...  
Keyword(s):  
Dna Synthesis ◽  
Rat Liver ◽  
S Phase ◽  
Cdk2 Activity ◽  
Regenerating Rat Liver ◽  
Phase Entry

Inhibition of in vivo DNA synthesis in regenerating rat liver following thermal injury

1989 ◽  
Vol 160 (1) ◽  
pp. 196-201 ◽  
Author(s):  
Edward A. Carter ◽  
Sara E. Kirkham ◽  
Ronald G. Tompkins ◽  
John F. Burke
Keyword(s):  
Dna Synthesis ◽  
Rat Liver ◽  
Thermal Injury ◽  
Regenerating Rat Liver
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