Sleep patterns and blood pressure variability in patients with pure autonomic failure

1991 ◽  
Vol 1 (4) ◽  
pp. 309-315 ◽  
Author(s):  
J. H. M. Tulen ◽  
A. J. Man in 't Veld ◽  
H. G. van Steenis ◽  
K. Mechelse
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Variability ◽  
Autonomic Failure ◽  
Pure Autonomic Failure ◽  
Sleep Patterns

Blood Pressure Variability in Health, Hypertension and Autonomic Failure

1985 ◽  
Vol 7 (2-3) ◽  
pp. 187-194 ◽  
Author(s):  
Stewart Mann ◽  
Michael W. Millar Craig ◽  
Douglas G. Altman ◽  
E. B. Raftery ◽  
S. N. Hunyor
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Variability ◽  
Autonomic Failure

Differential responses in superior mesenteric artery blood flow may explain the variant pressor responses to clonidine in two groups with sympathetic denervation

1992 ◽  
Vol 83 (1) ◽  
pp. 59-64 ◽  
Author(s):  
T. N. Thomaides ◽  
K. Ray Chaudhuri ◽  
S. Maule ◽  
C. J. Mathias
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Multiple System Atrophy ◽  
Superior Mesenteric Artery ◽  
Mesenteric Artery ◽  
Autonomic Failure ◽  
Pure Autonomic Failure ◽  
Artery Blood Flow ◽  
Control Subjects ◽  
Mesenteric Artery Blood Flow

1. Measurement of superior mesenteric artery blood flow along with systemic and regional haemodynamic changes in blood pressure, heart rate, cardiac index, forearm blood flow, digital skin blood flow and index finger temperature were made before and after administration of clonidine (2 μg/kg body weight intravenously) in 10 patients with multiple-system atrophy, 10 patients with pure autonomic failure and 15 age-matched healthy control subjects. 2. After clonidine, blood pressure fell in patients with multiple-system atrophy and control subjects but not in patients with pure autonomic failure. 3. Resting superior mesenteric artery blood flow was similar in patients with multiple-system atrophy and control subjects, but was higher in patients with pure autonomic failure. The fall in blood pressure after clonidine was accompanied by active dilatation of the superior mesenteric artery in patients with multiple-system atrophy and control subjects. This did not occur in patients with pure autonomic failure. 4. After clonidine, there was a fall in cardiac index in patients with multiple-system atrophy. 5. After clonidine, changes in other haemodynamic parameters were not significant in any group, except for a fall in forearm blood flow and a rise in index finger temperature in control subjects. 6. We conclude that after clonidine there are differential superior mesenteric artery blood flow responses in the two groups with autonomic failure (multiple-system atrophy and pure autonomic failure). These may relate to differences in the site of the sympathetic lesion, which is considered to be mainly central in multiple-system atrophy but peripheral in pure autonomic failure. The blood pressure responses to clonidine in the two groups may be largely dependent on changes in superior mesenteric artery blood flow.

Efficiency of droxydopa in pure autonomic failure

2010 ◽  
Vol 41 (01) ◽  
Author(s):  
M Knosalla ◽  
CA Haensch ◽  
J Wehe ◽  
H Lerch ◽  
J Weis ◽  
...  
Keyword(s):  
Autonomic Failure ◽  
Pure Autonomic Failure
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