Symmetric interspecies hybrids of mouse and human hemoglobin: Molecular basis of their abnormal oxygen affinity

1995 ◽  
Vol 14 (2) ◽  
pp. 81-88 ◽  
Author(s):  
Rajendra Prasad Roy ◽  
Parimala Nacharaju ◽  
Ronald L. Nagel ◽  
A. Seetharama Acharya
Keyword(s):  
Molecular Basis ◽  
Oxygen Affinity ◽  
Human Hemoglobin ◽  
Interspecies Hybrids

Understanding the molecular basis of the high oxygen affinity variant human hemoglobin Coimbra

2018 ◽  
Vol 637 ◽  
pp. 73-78 ◽  
Author(s):  
S.E. Jorge ◽  
M. Bringas ◽  
A.A. Petruk ◽  
M. Arrar ◽  
M.A. Marti ◽  
...  
Keyword(s):  
Molecular Basis ◽  
Oxygen Affinity ◽  
High Oxygen ◽  
Human Hemoglobin ◽  
High Oxygen Affinity

scholarly journals THE EFFECT OF FORMALDEHYDE ON THE OXYGEN EQUILIBRIUM OF HEMOGLOBIN

1954 ◽  
Vol 37 (6) ◽  
pp. 775-780 ◽  
Author(s):  
Karl F. Guthe
Keyword(s):  
Oxygen Pressure ◽  
Oxygen Affinity ◽  
Sulfhydryl Groups ◽  
Human Hemoglobin ◽  
Hill’S Equation ◽  
Oxygen Equilibrium ◽  
Hill's Equation ◽  
Hemoglobin Molecule

1. When formaldehyde (0.10 M) is added to solutions of human hemoglobin, the oxygen affinity of the hemoglobin increases considerably (more than tenfold near pH 7). The interaction between hemes of the same hemoglobin molecule decreases, as shown by a drop in the value of n in Hill's equation from 2.9 to 1.5 or less. 2. In the presence of formaldehyde, both n and the oxygen pressure for half-saturation fall gradually as the pH rises in the range from pH 6.2 to 7.2. 3. Some of the effect of formaldehyde on the oxygen equilibrium may be due to combination with sulfhydryl groups of the protein, but nitrogenous groups are probably also involved.

Hemoglobin Legnano (α2141 (HC3) Arg → Leu β2): A New Abnormal Human Hemoglobin with High Oxygen Affinity

Hemoglobin ◽  
1978 ◽  
Vol 2 (3) ◽  
pp. 249-259 ◽  
Author(s):  
F. Mavilio ◽  
M. Marinucci ◽  
L. Tentori ◽  
P. P. Fontanarosa ◽  
U. Rossi ◽  
...  
Keyword(s):  
Oxygen Affinity ◽  
High Oxygen ◽  
Human Hemoglobin ◽  
High Oxygen Affinity

Structure and Oxygen Affinity of Crystalline of DesArg141α Human Hemoglobin A in the T State

1995 ◽  
Vol 248 (1) ◽  
pp. 136-150 ◽  
Author(s):  
Jeffrey S. Kavanaugh ◽  
David R. Chafin ◽  
Arthur Arnone ◽  
Andrea Mozzarelli ◽  
Claudio Rivetti ◽  
...  
Keyword(s):  
Oxygen Affinity ◽  
Human Hemoglobin ◽  
Hemoglobin A ◽  
T State

scholarly journals Molecular Basis for Heme Extraction of the Antimicrobial Target IsdH from Staphylococcus aureus from Human Hemoglobin

2020 ◽  
Vol 118 (3) ◽  
pp. 195a
Author(s):  
Sandra Valenciano Bellido ◽  
Vu T. Nhuan ◽  
Makoto Nakakido ◽  
Jose M.M. Caaveiro ◽  
Kouhei Tsumoto
Keyword(s):  
Staphylococcus Aureus ◽  
Molecular Basis ◽  
Human Hemoglobin

scholarly journals Mixtures of tense and relaxed state polymerized human hemoglobin regulate oxygen affinity and tissue construct oxygenation

PLoS ONE ◽  
2017 ◽  
Vol 12 (10) ◽  
pp. e0185988 ◽  
Author(s):  
Donald Andrew Belcher ◽  
Uddyalok Banerjee ◽  
Christopher Michael Baehr ◽  
Kristopher Emil Richardson ◽  
Pedro Cabrales ◽  
...  
Keyword(s):  
Oxygen Affinity ◽  
Human Hemoglobin ◽  
Tissue Construct

scholarly journals Tertiary and quaternary structural basis of oxygen affinity in human hemoglobin as revealed by multiscale simulations

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Mauro Bringas ◽  
Ariel A. Petruk ◽  
Darío A. Estrin ◽  
Luciana Capece ◽  
Marcelo A. Martí
Keyword(s):  
Oxygen Affinity ◽  
Structural Basis ◽  
Multiscale Simulations ◽  
Human Hemoglobin

Magnesium(II) and Zinc(II)-protoporphyrin IX’s stabilize the lowest oxygen affinity state of human hemoglobin even more strongly than deoxyheme 1 1Edited by K. Nagai

1999 ◽  
Vol 292 (5) ◽  
pp. 1121-1136 ◽  
Author(s):  
Gentaro Miyazaki ◽  
Hideki Morimoto ◽  
Kyung-Mook Yun ◽  
Sam-Yong Park ◽  
Atushi Nakagawa ◽  
...  
Keyword(s):  
Oxygen Affinity ◽  
Human Hemoglobin

scholarly journals Structure and Oxygen Affinity of Crystalline des-His-146β Human Hemoglobin in the T State

1997 ◽  
Vol 272 (52) ◽  
pp. 33077-33084 ◽  
Author(s):  
Stefano Bettati ◽  
Laura D. Kwiatkowski ◽  
Jeffrey S. Kavanaugh ◽  
Andrea Mozzarelli ◽  
Arthur Arnone ◽  
...  
Keyword(s):  
Oxygen Affinity ◽  
Human Hemoglobin ◽  
T State
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