Comparison of newβ-adrenergic blockers, C-3, Kö1366, Y-6124 and YB-2, with pindolol and propranolol in the blood perfused canine papillary muscle preparation

1972 ◽  
Vol 28 (7) ◽  
pp. 813-814 ◽  
Author(s):  
T. Kimura ◽  
M. Endoh ◽  
N. Taira ◽  
K. Hashimoto
Keyword(s):  
Papillary Muscle ◽  
Muscle Preparation ◽  
Adrenergic Blockers

Convenient apparatus for recording contractions of isolated heart muscle

1965 ◽  
Vol 20 (4) ◽  
pp. 755-757 ◽  
Author(s):  
John R. Blinks
Keyword(s):  
Papillary Muscle ◽  
Heart Muscle ◽  
Isolated Heart ◽  
Organ Bath ◽  
Muscle Preparation ◽  
Isolated Atria ◽  
Double Muscle ◽  
Stimulating Electrodes ◽  
Chronotropic Effects ◽  
Isolated Organ Bath

A simple and convenient apparatus for physiological or pharmacological experiments on preparations of isolated heart muscle is described. Provision is made for recording independently from two preparations mounted in the same bath. Electrodes for stimulation or recording are incorporated in the clamps that hold the tissue. The construction ensures the maintenance of a high oxygen tension at the surface of the tissue without the mechanical artifacts that result from bubbling oxygen directly past it. papillary muscle; isolated organ bath; isolated atria; double muscle preparation; circulating salt solution; stimulating electrodes; concentration-effect curves; inotropic and chronotropic effects; oxygenation Submitted on November 5, 1964

Sign in / Sign up

Export Citation Format

Share Document