Increase of albumin, eosinophil cationic protein, histamine, leukotrienes and mast cell tryptase in nasal lavage fluid after challenge with inhalant allergen extract

1992 ◽  
Vol 36 (S2) ◽  
pp. C421-C424 ◽  
Author(s):  
A. W. Toorenenbergen ◽  
R. G. Wijk ◽  
A. M. Vermeulen ◽  
F. J. Zijlstra
Keyword(s):  
Mast Cell ◽  
Eosinophil Cationic Protein ◽  
Lavage Fluid ◽  
Nasal Lavage ◽  
Allergen Extract ◽  
Inhalant Allergen ◽  
Mast Cell Tryptase ◽  
Cationic Protein ◽  
Nasal Lavage Fluid

scholarly journals Inflammatory mediators in nasal lavage among school-age children from urban and rural areas in São Paulo, Brazil

2004 ◽  
Vol 122 (5) ◽  
pp. 204-207 ◽  
Author(s):  
Clóvis Eduardo Santos Galvão ◽  
Paulo Hilário Nascimento Saldiva ◽  
Jorge Elias Kalil Filho ◽  
Fábio Fernandes Morato Castro
Keyword(s):  
Urban Area ◽  
Rural Area ◽  
Nasal Mucosa ◽  
Eosinophil Cationic Protein ◽  
Lavage Fluid ◽  
Nasal Lavage ◽  
Rural Children ◽  
Cationic Protein ◽  
Nasal Airways ◽  
Nasal Lavage Fluid

CONTEXT: Some studies have shown that inflammatory processes in the nasal air passages may reflect or affect those in the lower airways. We decided to indirectly assess the inflammatory status of the nasal airways in two groups of children with different sensitization rates to aeroallergens. OBJECTIVE: To compare the inflammatory activity in the nasal airways, through the determination of mediators in nasal lavage fluid in two distinct populations. TYPE OF STUDY: Cross-sectional study. SETTING: Two public elementary schools, one in an urban setting and the other in a rural setting of the State of São Paulo, Brazil. METHODS: Two groups of 40 elementary school children with different sensitization rates to aeroallergens were formed. Samples of nasal lavage fluid were assessed for eosinophil cationic protein (ECP) and tryptase. Non-parametric tests were used for statistical analysis. RESULTS: Significantly higher levels of ECP were observed among students living in the urban area than those in the rural area (p < 0.05). No significant difference in the tryptase levels was observed. Also, the urban children who were sensitized to aeroallergens presented higher levels of ECP in nasal mucosa than the non-sensitized children, while this difference was not observed among the rural children. DISCUSSION: The lack of mast cell activity and increased eosinophil degranulation revealed a chronic inflammatory state in the nasal air passages. The higher eosinophil activity in the urban area, coinciding with higher sensitization to aeroallergens, suggests that there must be some factors in the urban area that can modulate airway inflammation by influencing the activation of inflammatory cells. CONCLUSION: Our findings showed that there was no difference in the concentrations of tryptase in nasal lavage fluids between the two studied groups. However, the children from the urban area presented with higher concentrations of eosinophil cationic protein than did those from the rural area. Also, the urban children who were sensitized to aeroallergens presented with greater concentrations of eosinophil cationic protein in nasal mucosa than the non-sensitized children, while this difference was not observed among the rural children.

Eosinophil Cationic Protein (ECP) and Tryptase in the Nasal lavage Fluid (NLF) of Children with Grass Pollen Rhinitis: levocabastine Effect

1998 ◽  
Vol 19 (2) ◽  
pp. 75-80 ◽  
Author(s):  
Roberto Bernardini ◽  
Elio Novembre ◽  
Luca Mugnaini ◽  
Maria Elisabetta Rossi ◽  
Alberto Vierucci
Keyword(s):  
Grass Pollen ◽  
Eosinophil Cationic Protein ◽  
Lavage Fluid ◽  
Nasal Lavage ◽  
Cationic Protein ◽  
Nasal Lavage Fluid

Allergen-induced increase of eosinophil cationic protein in nasal lavage fluid: Effect of the glucocorticoid budesonide

1990 ◽  
Vol 85 (5) ◽  
pp. 891-895 ◽  
Author(s):  
Hans Bisgaard ◽  
Henrik Grønborg ◽  
Niels Mygind ◽  
Ronald Dahl ◽  
Nils Lindqvist ◽  
...  
Keyword(s):  
Eosinophil Cationic Protein ◽  
Lavage Fluid ◽  
Nasal Lavage ◽  
Cationic Protein ◽  
Nasal Lavage Fluid

Nasal lavage fluid eosinophil cationic protein gradient reflects the eosinophilic inflammation in RSV infection

2007 ◽  
Vol &NA; ◽  
pp. S188
Author(s):  
N. Okamoto ◽  
M. Takasugi ◽  
E. Yoshimura ◽  
N. Takahashi ◽  
I. Nosjima ◽  
...  
Keyword(s):  
Eosinophil Cationic Protein ◽  
Lavage Fluid ◽  
Nasal Lavage ◽  
Eosinophilic Inflammation ◽  
Cationic Protein ◽  
Rsv Infection ◽  
Nasal Lavage Fluid

scholarly journals Endotyping of chronic rhinosinusitis with nasal polyp based on eosinophil, mast cell and basophil microparticles in nasal lavage fluid

2020 ◽  
Vol 145 (2) ◽  
pp. AB170
Author(s):  
Toru Takahashi ◽  
Atsushi Kato ◽  
Lydia Suh ◽  
Roderick Carter ◽  
Kathleen Harris ◽  
...  
Keyword(s):  
Mast Cell ◽  
Chronic Rhinosinusitis ◽  
Nasal Polyp ◽  
Lavage Fluid ◽  
Nasal Lavage ◽  
Nasal Lavage Fluid

Serum Eosinophil Cationic Protein is Superior to Mast Cell Tryptase as Marker for Response to Topical Corticosteroid Therapy in Eosinophilic Esophagitis

2014 ◽  
Vol 48 (7) ◽  
pp. 600-606 ◽  
Author(s):  
Christoph Schlag ◽  
Sabrina Pfefferkorn ◽  
Knut Brockow ◽  
Bernhard Haller ◽  
Julia Slotta-Huspenia ◽  
...  
Keyword(s):  
Mast Cell ◽  
Topical Corticosteroid ◽  
Corticosteroid Therapy ◽  
Eosinophilic Esophagitis ◽  
Eosinophil Cationic Protein ◽  
Mast Cell Tryptase ◽  
Cationic Protein

Demonstration of mast-cell chemotactic activity in nasal lavage fluid: characterization of one chemotaxin as c-kit ligand, stem cell factor

Allergy ◽  
1998 ◽  
Vol 53 (9) ◽  
pp. 874-879 ◽  
Author(s):  
G. Nilsson ◽  
M. Hjertson ◽  
M. Andersson ◽  
L. Greiff ◽  
C. Svensson ◽  
...  
Keyword(s):  
Mast Cell ◽  
Stem Cell ◽  
Stem Cell Factor ◽  
Lavage Fluid ◽  
Chemotactic Activity ◽  
Nasal Lavage ◽  
Kit Ligand ◽  
Nasal Lavage Fluid ◽  
Fluid Characterization
Sign in / Sign up

Export Citation Format

Share Document