Chiral separation of amino acids by capillary electrophoresis with 3-[(3-cholamidopropyl)-dimethylammonio]-1-propane sulfonate as chiral selector

2003 ◽  
Vol 57 (1-2) ◽  
pp. 81-86 ◽  
Author(s):  
C. D. Tran ◽  
J. Kang
Keyword(s):  
Amino Acids ◽  
Capillary Electrophoresis ◽  
Chiral Separation ◽  
Chiral Selector

Chiral separation of lobeline and benzhexol by capillary electrophoresis using the reaction mixture of β-cyclodextrin, phosphorous-pentoxide and l-glutamic acid as chiral selector

2001 ◽  
Vol 431 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Xiuli Lin ◽  
Guanbin Li ◽  
Wenqiang Jiang ◽  
Yongbao Chu ◽  
Pei Wu ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Glutamic Acid ◽  
Chiral Separation ◽  
Chiral Selector ◽  
Phosphorous Pentoxide

Chiral separation of dansyl-amino acids in a nonaqueous medium by capillary electrophoresis

1996 ◽  
Vol 737 (2) ◽  
pp. 263-272 ◽  
Author(s):  
István E. Valkó ◽  
Heli Sirén ◽  
Marja-Liisa Riekkola
Keyword(s):  
Amino Acids ◽  
Capillary Electrophoresis ◽  
Chiral Separation ◽  
Nonaqueous Medium ◽  
Dansyl Amino Acids

Use of neutral capillaries for the enantioseparation ofN-benzoylated amino acids by capillary electrophoresis with bromobalhimycin as chiral selector

2013 ◽  
Vol 36 (9-10) ◽  
pp. 1568-1574 ◽  
Author(s):  
Yongbo Peng ◽  
Tingting Zhang ◽  
Tingting Wang ◽  
Zhenghua Liu ◽  
Jacques Crommen ◽  
...  
Keyword(s):  
Amino Acids ◽  
Capillary Electrophoresis ◽  
Chiral Selector

Cationic permethylated 6-monoamino-6-monodeoxy-β-cyclodextrin as chiral selector of dansylated amino acids in capillary electrophoresis

2014 ◽  
Vol 99 ◽  
pp. 16-21 ◽  
Author(s):  
Krisztina Németh ◽  
Celesztina Domonkos ◽  
Virág Sarnyai ◽  
Julianna Szemán ◽  
László Jicsinszky ◽  
...  
Keyword(s):  
Amino Acids ◽  
Capillary Electrophoresis ◽  
Chiral Selector ◽  
Dansylated Amino Acids

scholarly journals Enantioseparation and Determination of Mephedrone and Its Metabolites by Capillary Electrophoresis Using Cyclodextrins as Chiral Selectors

Molecules ◽  
2020 ◽  
Vol 25 (12) ◽  
pp. 2879
Author(s):  
Pavel Řezanka ◽  
Denisa Macková ◽  
Radek Jurok ◽  
Michal Himl ◽  
Martin Kuchař
Keyword(s):  
Capillary Electrophoresis ◽  
Chiral Separation ◽  
Simplex Method ◽  
Background Electrolyte ◽  
Detection Limits ◽  
Chiral Selector ◽  
Designer Drug ◽  
Optimal Composition ◽  
Linear Calibration

Mephedrone, a psychoactive compound derived from cathinone, is widely used as a designer drug. The determination of mephedrone and its metabolites is important for understanding its possible use in medicine. In this work, a method of capillary electrophoresis for the chiral separation of mephedrone and its metabolites was developed. Carboxymethylated β-cyclodextrin was selected as the most effective chiral selector from seven tested cyclodextrin derivates. Based on the simplex method, the optimal composition of the background electrolyte was determined: at pH 2.75 and 7.5 mmol·L−1 carboxymethylated β-cyclodextrin the highest total resolution of a mixture of analytes was achieved. For mephedrone and its metabolites, calibration curves were constructed in a calibration range from 0.2 to 5 mmol·L−1; limits of detection, limits of quantification, precision, and repeatability were calculated, and according to Mandel’s fitting test, the linear calibration ranges were determined.

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