Metabolic and genetic control of isoenzyme spectrum of alkaline phosphatase inEscherichia coli

1978 ◽  
Vol 23 (1) ◽  
pp. 30-36 ◽  
Author(s):  
M. A. Nesmeyanova ◽  
O. B. Marayeva ◽  
A. I. Severin ◽  
I. S. Kulaybv
1961 ◽  
Vol 3 (4) ◽  
pp. 425-438 ◽  
Author(s):  
H. Echols ◽  
A. Garen ◽  
S. Garen ◽  
A. Torriani

Evolution ◽  
1985 ◽  
Vol 39 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Daniel E. Dykhuizen ◽  
Christy Mudd ◽  
Ann Honeycutt ◽  
Daniel L. Hartl

2009 ◽  
Vol 8 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Yoshinori Tamaki ◽  
Shozo Watanabe ◽  
Sachiko Moriuchi

Genetics ◽  
1979 ◽  
Vol 93 (3) ◽  
pp. 625-643
Author(s):  
Robert L Metzenberg ◽  
William Chia

ABSTRACT Mutants called nuc-1C, constitutive for alkaline phosphatase synthesis, were isolated and mapped very close to nuc-1 mutants in which this enzyme is not expressed. nuc-1 is epistatic to nuc-1C. nuc-1C acts only if it is cis to normal nuc-1 function. The preparation of partial diploids heterozygous for various nuc-1 alleles is described; nuc-1C is dominant to nuc-1+, which in turn is dominant to nuc-1. In heterocaryons with nuc-1+, nuc-1C is dominant when it is present in high proportion, but essentially recessive if it is present in low proportions. In heterocaryons with nuc-1, nuc-1C is again dominant when present in high proportions, but in low proportions it "complements" to give essentially normal repressibility. A model of regulation consistent with these findings is presented.


Sign in / Sign up

Export Citation Format

Share Document