3D-QSAR studies and pharmacophore identification of AT1 receptor antagonists

2015 ◽  
Vol 25 (1) ◽  
pp. 51-61 ◽  
Author(s):  
Miralem Smajić ◽  
Katarina Nikolić ◽  
Zorica Vujić ◽  
Lejla Ahmetović ◽  
Vesna Kuntić
Keyword(s):  
3D Qsar ◽  
At1 Receptor ◽  
Receptor Antagonists ◽  
Qsar Studies ◽  
Pharmacophore Identification ◽  
At1 Receptor Antagonists

A 3D-QSAR of Angiotensin II (AT1) Receptor Antagonists Based on Receptor Surface Analysis.

ChemInform ◽  
2004 ◽  
Vol 35 (17) ◽  
Author(s):  
Prasanna A. Datar ◽  
Prashant V. Desai ◽  
Evans C. Coutinho
Keyword(s):  
Angiotensin Ii ◽  
Surface Analysis ◽  
3D Qsar ◽  
At1 Receptor ◽  
Receptor Antagonists ◽  
At1 Receptor Antagonists

Exploration of 6,7-dimethoxyquinazoline derivatives as dual acting α1- and AT1-receptor antagonists: synthesis, evaluation, pharmacophore & 3D-QSAR modeling and receptor docking studies

RSC Advances ◽  
2016 ◽  
Vol 6 (36) ◽  
pp. 30661-30682 ◽  
Author(s):  
Neetesh Agrawal ◽  
Jatin Machhi ◽  
Virendra Rathwa ◽  
Ashish M. Kanhed ◽  
Sagar Patel ◽  
...  
Keyword(s):  
3D Qsar ◽  
Docking Studies ◽  
At1 Receptor ◽  
Receptor Antagonists ◽  
Qsar Modeling ◽  
At1 Receptor Antagonists

The 6,7-dimethoxyquinazoline scaffold was further explored to provide dual acting α1- and AT1-receptor antagonists by synthesizing a series of derivatives and biologically evaluating the newly synthesized compounds.

Synthesis of N-Alkyl-1,2,4-oxadiazinones as Angiotensin-II (AT1) Receptor Antagonists

Heterocycles ◽  
1993 ◽  
Vol 36 (5) ◽  
pp. 1027 ◽  
Author(s):  
Harold N. Weller ◽  
Arthur V. Miller ◽  
Kenneth E. J. Dickinson ◽  
S. Anders Hedberg ◽  
Carol L. Delaney ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
At1 Receptor ◽  
Receptor Antagonists ◽  
At1 Receptor Antagonists

Nitric Oxide-Dependent Antiplatelet Action of AT1-Receptor Antagonists in a Pulmonary Thromboembolism in Mice

2003 ◽  
Vol 42 (6) ◽  
pp. 710-713 ◽  
Author(s):  
Tomasz Matys ◽  
Iwona Kucharewicz ◽  
Robert Pawlak ◽  
Ewa Chabielska ◽  
Tomasz Domaniewski ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Pulmonary Thromboembolism ◽  
At1 Receptor ◽  
Receptor Antagonists ◽  
At1 Receptor Antagonists

Influence of the AT1 Receptor Antagonists Telmisartan and Losartan on Reproduction and Offspring After Paternal Exposure to Ionizing Radiation

2018 ◽  
Vol 26 (5) ◽  
pp. 639-648
Author(s):  
Ana Paula Cavalim Vale ◽  
Guilherme dos Santos ◽  
Teresa Prado da Silva ◽  
Naira da Silva Mansano ◽  
Agnaldo Bruno Chies ◽  
...  
Keyword(s):  
Ionizing Radiation ◽  
At1 Receptor ◽  
Receptor Antagonists ◽  
Paternal Exposure ◽  
At1 Receptor Antagonists
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