Molecular modelling studies for the discovery of new substituted pyridines derivatives with angiotensin II AT1 receptor antagonists

Substituted Pyridines ◽

Discovery of potent antihypertensive ligands substituted imidazolyl biphenyl sulfonylureas analogs as angiotensin II AT1 receptor antagonists by molecular modelling studies

Interdisciplinary Sciences Computational Life Sciences ◽

10.1007/s12539-013-0046-3 ◽

2014 ◽

Cited By ~ 2

Author(s):

Mukesh C. Sharma

Keyword(s):

Angiotensin Ii ◽

Molecular Modelling ◽

At1 Receptor ◽

Receptor Antagonists ◽

At1 Receptor Antagonists ◽

Discovery of Potent Antihypertensive Ligands Substituted Imidazolyl Biphenyl Sulfonylureas Analogs as Angiotensin II $$\hbox {AT}_{1}$$ AT 1 Receptor Antagonists by Molecular Modelling Studies

Interdisciplinary Sciences Computational Life Sciences ◽

10.1007/s12539-015-0006-1 ◽

2015 ◽

Vol 7 (3) ◽

pp. 221-232

Author(s):

Mukesh C. Sharma

Keyword(s):

Angiotensin Ii ◽

Molecular Modelling ◽

Receptor Antagonists ◽

Synthesis of N-Alkyl-1,2,4-oxadiazinones as Angiotensin-II (AT1) Receptor Antagonists

Heterocycles ◽

10.3987/com-92-6263 ◽

1993 ◽

Vol 36 (5) ◽

pp. 1027 ◽

Cited By ~ 12

Author(s):

Harold N. Weller ◽

Arthur V. Miller ◽

Kenneth E. J. Dickinson ◽

S. Anders Hedberg ◽

Carol L. Delaney ◽

...

Keyword(s):

Angiotensin Ii ◽

At1 Receptor ◽

Receptor Antagonists ◽

New pyrazolo[3,4-b]pyridones as selective A1 adenosine receptor antagonists: synthesis, biological evaluation and molecular modelling studies

Organic & Biomolecular Chemistry ◽

10.1039/b502831k ◽

2005 ◽

Vol 3 (12) ◽

pp. 2262 ◽

Cited By ~ 7

Author(s):

Paola Fossa ◽

Marco Pestarino ◽

Giulia Menozzi ◽

Luisa Mosti ◽

Silvia Schenone ◽

...

Keyword(s):

Molecular Modelling ◽

Adenosine Receptor ◽

Biological Evaluation ◽

Receptor Antagonists ◽

A1 Adenosine Receptor ◽

Effect of the AT1-Receptor Antagonists Losartan, Irbesartan, and Telmisartan on Angiotensin II-Induced Facilitation of Sympathetic Neurotransmission in the Rat Mesenteric Artery

Journal of Cardiovascular Pharmacology ◽

10.1097/00005344-200107000-00015 ◽

2001 ◽

Vol 38 (1) ◽

pp. 141-148 ◽

Cited By ~ 38

Author(s):

Jippe C. Balt ◽

Marie-Jeanne Mathy ◽

Alexander Nap ◽

Martin Pfaffendorf ◽

Pieter A. van Zwieten

Keyword(s):

Angiotensin Ii ◽

Mesenteric Artery ◽

At1 Receptor ◽

Receptor Antagonists ◽

Sympathetic Neurotransmission ◽

Rat Mesenteric Artery ◽

Distinction between surmountable and insurmountable selective AT1 receptor antagonists by use of CHO-K1 cells expressing human angiotensin II AT1 receptors

British Journal of Pharmacology ◽

10.1038/sj.bjp.0702398 ◽

1999 ◽

Vol 126 (4) ◽

pp. 1057-1065 ◽

Cited By ~ 115

Author(s):

P M L Vanderheyden ◽

F L P Fierens ◽

J P De Backer ◽

N Fraeyman ◽

G Vauquelin

Keyword(s):

Angiotensin Ii ◽

At1 Receptor ◽

Receptor Antagonists ◽

At1 Receptors ◽

Quantitative structure activity relationship analysis of angiotensin II AT1 receptor antagonists

Medicinal Chemistry Research ◽

10.1007/s00044-009-9205-9 ◽

2009 ◽

Vol 19 (5) ◽

pp. 475-489 ◽

Cited By ~ 9

Author(s):

Sarvesh Kumar Paliwal ◽

Mahima Pal ◽

Anees A. Siddiqui

Keyword(s):

Angiotensin Ii ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

At1 Receptor ◽

Activity Relationship ◽

Quantitative Structure ◽

Receptor Antagonists ◽

Relationship Analysis ◽

Structure Activity ◽

A comparative molecular field analysis and molecular modelling studies on pyridylimidazole type of angiotensin II antagonists

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(99)00245-x ◽

1999 ◽

Vol 7 (12) ◽

pp. 2971-2976 ◽

Cited By ~ 14

Author(s):

Sung-eun Yoo ◽

Soo-Kyung Kim ◽

Sung-Hou Lee ◽

Kyu Yang Yi ◽

Dai-Woon Lee

Keyword(s):

Angiotensin Ii ◽

Molecular Modelling ◽

Field Analysis ◽

Molecular Field ◽

Comparative Molecular Field Analysis ◽

Molecular Field Analysis ◽

Angiotensin Ii Antagonists ◽

Angiotensin II AT1 receptor antagonists and platelet activation

Nephrology Dialysis Transplantation ◽

10.1093/ndt/16.suppl_1.45 ◽

2001 ◽

Vol 16 (suppl_1) ◽

pp. 45-49 ◽

Cited By ~ 30

Author(s):

Antonio López‐Farré ◽

Lourdes Sánchez de Miguel ◽

Mercedes Montón ◽

Ana Jiménez ◽

Almudena Lopez‐Bloya ◽

...

Keyword(s):

Angiotensin Ii ◽

Platelet Activation ◽

At1 Receptor ◽

Receptor Antagonists ◽

Comparative QSAR and pharmacophore analysis for a series of 2,4-dihydro-3H-1,2,4-triazol-3-ones derivatives as angiotensin II AT1 receptor antagonists

Medicinal Chemistry Research ◽

10.1007/s00044-013-0831-x ◽

2013 ◽

Vol 23 (5) ◽

pp. 2486-2502 ◽

Cited By ~ 5

Author(s):

Mukesh C. Sharma ◽

Smita Sharma ◽

Pratibha Sharma ◽

Ashok Kumar ◽

Kamlendra Singh Bhadoriya

Keyword(s):

Angiotensin Ii ◽

At1 Receptor ◽

Receptor Antagonists ◽