Regioselective one pot synthesis of 1,2,3-triazole derivatives bearing phthalazine moiety and their pharmacological activity

2016 ◽  
Vol 25 (11) ◽  
pp. 2680-2690 ◽  
Author(s):  
P. C. Shyma ◽  
Balakrishna Kalluraya ◽  
S. K. Peethambar ◽  
A. M. Vijesh
ChemInform ◽  
2010 ◽  
Vol 42 (3) ◽  
pp. no-no
Author(s):  
Sheng-Jiao Yan ◽  
Yong-Jiang Liu ◽  
Yu-Lan Chen ◽  
Lin Liu ◽  
Jun Lin

2010 ◽  
Vol 20 (17) ◽  
pp. 5225-5228 ◽  
Author(s):  
Sheng-Jiao Yan ◽  
Yong-Jiang Liu ◽  
Yu-Lan Chen ◽  
Lin Liu ◽  
Jun Lin

ACS Omega ◽  
2021 ◽  
Vol 6 (39) ◽  
pp. 25574-25584
Author(s):  
Zeinab A. Hozien ◽  
Ahmed F. M. EL-Mahdy ◽  
Laila S. A. Ali ◽  
Ahmad Abo Markeb ◽  
Hassan A. H. El-Sherief

2014 ◽  
Vol 20 (6) ◽  
Author(s):  
Ayşegül Gümüş ◽  
Sibel Uçur

AbstractThe one-pot synthesis of novel 1,4-disubstituted 1,2,3-triazole derivatives derived from homopropargyl alcohol backbones has been accomplished. Triazoles are obtained in good yields from a variety of readily available aromatic and aliphatic halides without isolation of potentially unstable organic azide intermediates.


Synlett ◽  
2018 ◽  
Vol 29 (05) ◽  
pp. 673-677 ◽  
Author(s):  
Zhen Chen ◽  
Chunmei Han ◽  
Suping Dong ◽  
Wensheng Zhang

A one-pot synthesis of 1-monosubstituted-1,2,3-triazoles from propargyl alcohol and various aryl azides was achieved. This simple method provides concise and efficient access to various 1-monosubstituted 1,2,3-triazole derivatives through a three-step one-pot ­sequence in good to excellent yields.


2014 ◽  
Vol 10 ◽  
pp. 3031-3037 ◽  
Author(s):  
Kuppusamy Bharathimohan ◽  
Thanasekaran Ponpandian ◽  
A Jafar Ahamed ◽  
Nattamai Bhuvanesh

Herein, we describe a one-pot protocol for the synthesis of a novel series of polycyclic triazole derivatives. Transition metal-catalyzed decarboxylative CuAAC and dehydrogenative cross coupling reactions are combined in a single flask and achieved good yields of the respective triazoles (up to 97% yield). This methodology is more convenient to produce the complex polycyclic molecules in a simple way.


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