Daily fluctuation of hepatic P450 monooxygenase activities in male rats is controlled by the suprachiasmatic nucleus but remains unaffected by adrenal hormones

1999 ◽  
Vol 73 (7) ◽  
pp. 367-372 ◽  
Author(s):  
Tadashi Furukawa ◽  
Sunao Manabe ◽  
Toshiyuki Watanabe ◽  
Shinya Sehata ◽  
Satoru Sharyo ◽  
...  
1984 ◽  
Vol 103 (3) ◽  
pp. 295-300 ◽  
Author(s):  
S. D. H. Chan ◽  
D. K. H. Chiu ◽  
D. Atkins

ABSTRACT The distribution of 1α,25-dihydroxyvitamin D3 (1,25-(OH)2D3) receptors in isolated jejunal villous and crypt cells was investigated in normal and adrenalectomized male rats, and also in animals treated with the synthetic glucocorticoid, dexamethasone, and/or the glucocorticoid antagonist, 11-deoxycortisol. Adrenalectomy caused an increase in 1,25-(OH)2D3 receptors whilst dexamethasone treatment led to a reduction in receptor number. 11-Deoxycortisol was able to reverse the 'down-regulation' effect caused by glucocorticoids. In all cases, the changes in receptor numbers were more pronounced in crypt cells. The data suggest that, in the small intestine, glucocorticoids may control the synthesis of 1,25-(OH)2D3 receptors via the mediation of a glucocorticoid receptor, and that the adrenal hormones mainly express their effect in crypt cells. It is proposed that this phenomenon may, in part, explain the reduction in calcium absorption which occurs in man after chronic glucocorticoid treatment. J. Endocr. (1984) 103, 295–300


Author(s):  
Somaye Mesgar ◽  
Seyed Behnamedin Jameie ◽  
Abbas Aliaghaei ◽  
Siavash Parvardeh ◽  
Abolfazl Torabi ◽  
...  

1998 ◽  
Vol 792 (2) ◽  
pp. 343-347 ◽  
Author(s):  
Mario Engelmann ◽  
Karl Ebner ◽  
Rainer Landgraf ◽  
Carsten T Wotjak

Endocrinology ◽  
2014 ◽  
Vol 155 (2) ◽  
pp. 525-535 ◽  
Author(s):  
M. Guzmán-Ruiz ◽  
N. Saderi ◽  
F. Cazarez-Márquez ◽  
N. N. Guerrero-Vargas ◽  
M. C. Basualdo ◽  
...  

1977 ◽  
Vol 122 (1) ◽  
pp. 33-47 ◽  
Author(s):  
Nobuo Ibuka ◽  
Shin-ichi T. Inouye ◽  
Hiroshi Kawamura

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