Quantitative assessment of hepatic blood flow using intravenous indocyanine green

2008 ◽  
Vol 64 (11) ◽  
pp. 1133-1134 ◽  
Author(s):  
Joseph D. Ma ◽  
Anne N. Nafziger ◽  
William Mylott ◽  
David B. Haughey ◽  
Mario L. Rocci ◽  
...  
Keyword(s):  
Blood Flow ◽  
Indocyanine Green ◽  
Hepatic Blood Flow ◽  
Quantitative Assessment

Rapid Infusion of Hydroxyethyl Starch 70/0.5 but not Acetate Ringer’s Solution Decreases the Plasma Concentration of Propofol during Target-controlled Infusion

2016 ◽  
Vol 125 (2) ◽  
pp. 304-312 ◽  
Author(s):  
Sayako Itakura ◽  
Kenichi Masui ◽  
Tomiei Kazama
Keyword(s):  
Blood Flow ◽  
Plasma Concentration ◽  
Indocyanine Green ◽  
Blood Volume ◽  
Hydroxyethyl Starch ◽  
Hepatic Blood Flow ◽  
Disappearance Rate ◽  
Rapid Infusion ◽  
Ringer’S Solution ◽  
Target Controlled Infusion

Abstract Background Rapid fluid infusion resulting in increased hepatic blood flow may decrease the propofol plasma concentration (Cp) because propofol is a high hepatic extraction drug. The authors investigated the effects of rapid colloid and crystalloid infusions on the propofol Cp during target-controlled infusion. Methods Thirty-six patients were randomly assigned to 1 of 3 interventions (12 patients per group). At least 30 min after the start of propofol infusion, patients received either a 6% hydroxyethyl starch (HES) solution at 24 ml·kg−1·h−1 or acetated Ringer’s solution at 24 or 2 ml·kg−1·h−1 during the first 20 min. In all groups, acetated Ringer’s solution was infused at 2 ml·kg−1·h−1 during the next 20 min. The propofol Cp was measured every 2.5 min as the primary outcome. Cardiac output, blood volume, and indocyanine green disappearance rate were determined using a pulse dye densitogram analyzer before and after the start of fluid administration. Effective hepatic blood flow was calculated as the blood volume multiplied by the indocyanine green disappearance rate. Results The rapid HES infusion significantly decreased the propofol Cp by 22 to 37%, compared to the Cp at 0 min, whereas the rapid or maintenance infusion of acetate Ringer’s solution did not decrease the propofol Cp. Rapid HES infusion, but not acetate Ringer’s solution infusion, increased the effective hepatic blood flow. Conclusions Rapid HES infusion increased the effective hepatic blood flow, resulting in a decreased propofol Cp during target-controlled infusion. Rapid HES infusion should be used cautiously as it may decrease the depth of anesthesia.

Nicardipine increases hepatic blood flow and the hepatic clearance of indocyanine green in patients with cirrhosis

1994 ◽  
Vol 20 (6) ◽  
pp. 792-796 ◽  
Author(s):  
Juan Carlos García-Pagán ◽  
Fausto Feu ◽  
Angelo Luca ◽  
Mercedes Fernández ◽  
Pilar Pizcueta ◽  
...  
Keyword(s):  
Blood Flow ◽  
Indocyanine Green ◽  
Hepatic Blood Flow ◽  
Hepatic Clearance

scholarly journals Hepatic blood flow: accuracy of estimation from infusions of indocyanine green in anaesthetized cats

1987 ◽  
Vol 91 (3) ◽  
pp. 651-659 ◽  
Author(s):  
F.J. Burczynski ◽  
C. V. Greenway ◽  
D.S. Sitar
Keyword(s):  
Blood Flow ◽  
Indocyanine Green ◽  
Hepatic Blood Flow

scholarly journals The Use of Indocyanine Green for Measuring Fetal Hepatic Blood Flow. † 263

1997 ◽  
Vol 41 ◽  
pp. 46-46
Author(s):  
Robert G Holcomb ◽  
Randall B Wilkening
Keyword(s):  
Blood Flow ◽  
Indocyanine Green ◽  
Hepatic Blood Flow
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