Local Administration of Antibiotics by Gentamycin–Collagene Sponge does not Improve Wound Healing or Reduce Recurrence Rate after Pilonidal Excision with Primary Suture. A Prospective Randomized Controlled Trial

2010 ◽  
Vol 34 (12) ◽  
pp. 3047-3048 ◽  
Author(s):  
Mark Cheetham
Keyword(s):  
Wound Healing ◽  
Randomized Controlled Trial ◽  
Recurrence Rate ◽  
Controlled Trial ◽  
Local Administration ◽  
Primary Suture ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial ◽  
Improve Wound Healing

Prospective randomized controlled trial comparing V–Y advancement flap with primary suture methods in pilonidal disease

2010 ◽  
Vol 199 (2) ◽  
pp. 170-177 ◽  
Author(s):  
Tarık Zafer Nursal ◽  
Ali Ezer ◽  
Kenan Çalışkan ◽  
Nurkan Törer ◽  
Sedat Belli ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Pilonidal Disease ◽  
Controlled Trial ◽  
Advancement Flap ◽  
Primary Suture ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial

scholarly journals Relapse after conservative surgery combined with Triptorelin Acetate versus conservative surgery only in women with focal adenomyosis: study protocol for a multicenter, prospective, randomized controlled trial

2019 ◽  
Author(s):  
Wenwen Wang ◽  
Xiangyi Ma ◽  
Wei Zhang ◽  
Zhiying Li ◽  
Yan Wang ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Recurrence Rate ◽  
Rating Scale ◽  
Short Form ◽  
Controlled Trial ◽  
Conservative Surgery ◽  
Postoperative Treatment ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial ◽  
Triptorelin Acetate

Abstract Background: To preserve fertility or integrity of organs was on the rise for the most women with adenomyosis. Adenomyomectomy is now a widely applied conservative surgery, however relapse is a serious problem after operation. Postoperative treatment, such as gonadotropin-releasing hormone agonist (GnRHa) has been suggested to result in reducing the recurrence rate in patients. However, there is still a lack of evidence from randomized clinical trials comparing the efficacy of GnRHa for decreasing the postoperative recurrence rate. Method/Design：Relapse after conservative surgery combined with Triptorelin Acetate versus conservative surgery only in women with focal adenomyosis is a multicenter, prospective, randomized controlled trial. The primary outcome is relapse accessed with Visual Analogue Scale (VRS) and Numeric Rating Scale (NRS), Pictorial blood loss assessment chart (PBAC) score and the size of uterus and lesion are measured by two/three-dimensional color doppler ultrasonography (2D/3D-CDUS) or magnetic resonance imaging (MRI). The secondary outcomes include quality of life, clinical pregnancy, ovarian reserve, and adverse events, assessing by Short Form (36) Health Survey and Female Sexual Function index, serum follicle-stimulating hormone, estradiol levels and anti-muellerian hormone and so on. All these indexes are measured at 3, 6, 12, 18, 24, 30, 36 months after conservative surgery. Discussion：The result of this large multicenter randomized trial will provide evidence for one of the strategies of long-term management in focal adenomyosis after conservative operation.

scholarly journals Relapse after conservative surgery combined with Triptorelin Acetate versus conservative surgery only in women with focal adenomyosis: study protocol for a multicenter, prospective, randomized controlled trial

2020 ◽  
Author(s):  
Wenwen Wang ◽  
Xiangyi Ma ◽  
Wei Zhang ◽  
Zhiying Li ◽  
Yan Wang ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Recurrence Rate ◽  
Rating Scale ◽  
Short Form ◽  
Controlled Trial ◽  
Conservative Surgery ◽  
Postoperative Treatment ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial ◽  
Triptorelin Acetate

Abstract Background: To preserve fertility or integrity of organs was on the rise for the most women with adenomyosis. Adenomyomectomy is now a widely applied conservative surgery, however relapse is a serious problem after operation. Postoperative treatment, such as gonadotropin-releasing hormone agonist (GnRHa) has been suggested to result in reducing the recurrence rate in patients. However, there is still a lack of evidence from randomized clinical trials comparing the efficacy of GnRHa for decreasing the postoperative recurrence rate. Method/Design：Relapse after conservative surgery combined with Triptorelin Acetate versus conservative surgery only in women with focal adenomyosis is a multicenter, prospective, randomized controlled trial. The primary outcome is relapse accessed with Visual Analogue Scale (VRS) and Numeric Rating Scale (NRS), Pictorial blood loss assessment chart (PBAC) score and the size of uterus and lesion are measured by two/three-dimensional color doppler ultrasonography (2D/3D-CDUS) or magnetic resonance imaging (MRI). The secondary outcomes include quality of life, clinical pregnancy, ovarian reserve, and adverse events, assessing by Short Form (36) Health Survey and Female Sexual Function index, serum follicle-stimulating hormone, estradiol levels and anti-muellerian hormone and so on. All these indexes are measured at 3, 6, 12, 18, 24, 30, 36 months after conservative surgery. Discussion：The result of this large multicenter randomized trial will provide evidence for one of the strategies of long-term management in focal adenomyosis after conservative operation.

scholarly journals Effect of oral nutritional supplementation on wound healing in diabetic foot ulcers: a prospective randomized controlled trial

2014 ◽  
Vol 31 (9) ◽  
pp. 1069-1077 ◽  
Author(s):  
D. G. Armstrong ◽  
J. R. Hanft ◽  
V. R. Driver ◽  
A. P. S. Smith ◽  
J. L. Lazaro‐Martinez ◽  
...  
Keyword(s):  
Wound Healing ◽  
Randomized Controlled Trial ◽  
Diabetic Foot ◽  
Controlled Trial ◽  
Nutritional Supplementation ◽  
Foot Ulcers ◽  
Diabetic Foot Ulcers ◽  
Randomized Controlled ◽  
Prospective Randomized Controlled Trial
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