Genetic mapping of 10 microsatellites in the t complex region of mouse Chromosome 17

1998 ◽  
Vol 9 (6) ◽  
pp. 472-472 ◽  
Author(s):  
Corine Vernet ◽  
Kuniya Abe ◽  
Karen Artzt
Keyword(s):  
Genetic Mapping ◽  
Mouse Chromosome ◽  
Chromosome 17 ◽  
Complex Region ◽  
T Complex

scholarly journals Identification of a human ortholog of the mouse Dcpp gene locus, encoding a novel member of the CSP-1/Dcpp salivary protein family

2006 ◽  
Vol 28 (1) ◽  
pp. 129-140 ◽  
Author(s):  
John J. Mullins ◽  
Linda J. Mullins ◽  
Donald R. Dunbar ◽  
William J. Brammar ◽  
Kenneth W. Gross ◽  
...  
Keyword(s):  
Amino Acid ◽  
Oral Cavity ◽  
Salivary Glands ◽  
Mouse Chromosome ◽  
Mrna Translation ◽  
Salivary Protein ◽  
Protein Family ◽  
Chromosome 17 ◽  
Complex Region ◽  
T Complex

Salivary fluid, the collective product of numerous major and minor salivary glands, contains a range of secretory proteins that play key defensive, digestive, and gustatory roles in the oral cavity. To understand the distinct protein “signature” contributed by individual salivary glands to salivary secretions, we studied a family of proteins shown by in vitro mRNA translation to be abundantly expressed in mouse sublingual glands. Molecular cloning, Southern blotting, and restriction fragment length polymorphism analyses showed these to represent one known and two novel members of the common salivary protein (CSP-1)/Demilune cell and parotid protein (Dcpp) salivary protein family, the genes for which are closely linked in the T-complex region of mouse chromosome 17. Bioinformatic analysis identified a putative human CSP-1/Dcpp ortholog, HRPE773, expressed predominantly in human salivary tissue, that shows 31% amino acid identity and 45% amino acid similarity to the mouse Dcpp query sequence. The corresponding human gene displays a similar structure to the mouse Dcpp genes and is located on human chromosome 16 in a region known to be syntenic with the T-complex region of mouse chromosome 17. The predicted mouse and human proteins both display classical NH2-terminal signal sequences, putative jacalin-related lectin domains, and potential N-linked glycosylation sites, suggesting secretion via sublingual saliva into the oral cavity where they may display antimicrobial activity or provide a defensive coating to enamel. Identification of a human CSP-1/Dcpp ortholog therefore provides a key tool for investigation of salivary protein function in human oral health and disease.

Genetic mapping of thet-complex region on mouse chromosome 17 including theHybrid sterility-1 gene

1991 ◽  
Vol 1 (2) ◽  
pp. 84-91 ◽  
Author(s):  
Jiři Forejt ◽  
Vladimir Vincek ◽  
Jan Klein ◽  
Hans Lehrach ◽  
Milada Loudová-Micková
Keyword(s):  
Genetic Mapping ◽  
Mouse Chromosome ◽  
Chromosome 17 ◽  
Complex Region

Molecular Studies of Mouse Chromosome 17 and the T Complex

1984 ◽  
pp. 141-156 ◽  
Author(s):  
Lee M. Silver ◽  
James I. Garrels ◽  
Hans Lehrach
Keyword(s):  
Mouse Chromosome ◽  
Chromosome 17 ◽  
T Complex ◽  
Molecular Studies

Genetic mapping of Ptprm on mouse Chromosome 17

1995 ◽  
Vol 6 (10) ◽  
pp. 757-758
Author(s):  
Y. Mukouyama ◽  
T. Watanabe ◽  
T. Kume ◽  
M. Oishi
Keyword(s):  
Genetic Mapping ◽  
Mouse Chromosome ◽  
Chromosome 17

Genetic mapping of the vascular endothelial growth factor (Vegf) gene to mouse Chromosome 17

1997 ◽  
Vol 8 (6) ◽  
pp. 451-452 ◽  
Author(s):  
L. De Gregorio ◽  
V. Vincenti ◽  
G. Breier ◽  
A. Damert ◽  
T. A. Dragani ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Genetic Mapping ◽  
Mouse Chromosome ◽  
Chromosome 17 ◽  
Vascular Endothelial ◽  
Vegf Gene ◽  
Endothelial Growth Factor

Location of the t complex on mouse chromosome 17 by in situ hybridization with Tcp-1

1986 ◽  
Vol 24 (2) ◽  
pp. 125-127 ◽  
Author(s):  
M. F. Lyon ◽  
J. Zenthon ◽  
E. P. Evansz ◽  
M. D. Burtenshaw ◽  
K. Dudley ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Mouse Chromosome ◽  
Chromosome 17 ◽  
T Complex

Genetic mapping of a male germ cell-expressed gene Tpx-2 to mouse chromosome 17

1991 ◽  
Vol 34 (2) ◽  
Author(s):  
Masanori Kasahara ◽  
Eric Seboun ◽  
Marc Fellous ◽  
JosephH. Nadeau
Keyword(s):  
Genetic Mapping ◽  
Germ Cell ◽  
Mouse Chromosome ◽  
Male Germ Cell ◽  
Chromosome 17

Zfp-51, a murine zinc finger encoding gene mapping to the t-complex region of Chromosome 17, encodes 19 contiguous zinc fingers and is ubiquitously expressed

1994 ◽  
Vol 5 (6) ◽  
pp. 387-389 ◽  
Author(s):  
P. S. Burke ◽  
J. Don ◽  
D. J. Wolgemuth
Keyword(s):  
Gene Mapping ◽  
Zinc Finger ◽  
Zinc Fingers ◽  
Chromosome 17 ◽  
Complex Region ◽  
T Complex ◽  
Encoding Gene

Mapping of the Sod-2 locus into the t complex on mouse chromosome 17

1988 ◽  
Vol 28 (4) ◽  
pp. 260-264 ◽  
Author(s):  
Felipe Figueroa ◽  
Vladimir Vincek ◽  
Masanori Kasahara ◽  
Graeme I. Bell ◽  
Jan Klein
Keyword(s):  
Mouse Chromosome ◽  
Chromosome 17 ◽  
T Complex
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