Wall or machine suction rectal biopsy for Hirschsprung’s disease: a simple modified technique can improve the adequacy of biopsy

2006 ◽  
Vol 22 (8) ◽  
pp. 681-682 ◽  
Author(s):  
A. E. Ali ◽  
J. A. Morecroft ◽  
J. C. Bowen ◽  
J. Bruce ◽  
A. Morabito
Keyword(s):  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Rectal Biopsy ◽  
Modified Technique ◽  
Suction Rectal Biopsy

scholarly journals Suction rectal biopsy in the diagnosis of Hirschsprung's disease and chronic constipation

1986 ◽  
Vol 1 (2) ◽  
pp. 84-89 ◽  
Author(s):  
Theodore Z. Polley ◽  
Arnold G. Coran ◽  
Kathleen P. Heidelberger ◽  
John R. Wesley
Keyword(s):  
Chronic Constipation ◽  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Rectal Biopsy ◽  
Suction Rectal Biopsy

Accuracy of Suction Rectal Biopsy for Diagnosis of Hirschsprung's Disease in Neonates

2018 ◽  
Vol 29 (05) ◽  
pp. 425-430 ◽  
Author(s):  
Ashley Rebekah Allen ◽  
Angelica R. Putnam ◽  
Angela P. Presson ◽  
Chelsea McCarty Allen ◽  
Douglas C. Barnhart ◽  
...  
Keyword(s):  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Age Groups ◽  
Newborn Infants ◽  
Rectal Biopsy ◽  
Suction Rectal Biopsy ◽  
Postmenstrual Age ◽  
Pull Through ◽  
One Year

Introduction Recent publications have questioned the sensitivity of suction rectal biopsy (SRB) for diagnosis of Hirschsprung's disease (HD) in newborns. A recent European survey reported that 39% of pediatric surgeons performed full-thickness transanal biopsies due to concerns about the accuracy of SRB. We sought to examine our contemporary SRB experience in infants. Materials and Methods A review was performed (2007–2016) of patients under 6 months of age who had a SRB at our children's hospital. The cohort was subdivided by postmenstrual age at time of SRB: preterm (< 40 weeks, A), term neonate (40–44 weeks, B), and infant (> 44 weeks, C). The pathology reports from endorectal pull-through were used as gold standard confirmation. One-year follow-up of patients with negative SRB was used to confirm accurate diagnosis. Results A total of 153 patients met the criteria and a total of 159 SRBs (< 2,500 g; n = 26) were performed (A = 60, B = 58, C = 35). Forty-three patients were diagnosed with HD (A = 25, B = 15, C = 3). A second SRB was performed in 6 (3.9%) patients due to inadequate tissue (A = 2, B = 2, C = 2) with HD diagnosed in 5. No complications occurred. Sensitivity and specificity of SRB was 100% in all age groups. Half of the patients with a negative SRB had at least 1 year follow-up, with none subsequently diagnosed with HD. Conclusion SRB results in adequate tissue for evaluation of HD in nearly all patients less than 6 months of age on the first attempt and is highly accurate in the preterm and newborn infants. No complications occurred, even among infants less than 2,500 g.

The Incidence of Hirschsprung's Disease in Premature Infants and the Role of Suction Rectal Biopsy

2013 ◽  
Vol 179 (2) ◽  
pp. 195
Author(s):  
J.P. Pettiford ◽  
S.R. Shah ◽  
P. Thomas ◽  
N. Sharp ◽  
D. Juang ◽  
...  
Keyword(s):  
Premature Infants ◽  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Rectal Biopsy ◽  
Suction Rectal Biopsy

Rectal Biopsy for Hirschsprung's Disease – Are We Performing too Many?

2010 ◽  
Vol 20 (02) ◽  
pp. 95-97 ◽  
Author(s):  
N. Rahman ◽  
J. Chouhan ◽  
S. Gould ◽  
Vt. Joseph ◽  
H. Grant ◽  
...  
Keyword(s):  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Rectal Biopsy

Diagnosing Hirschsprung's disease: Increasing the odds of a positive rectal biopsy result

2003 ◽  
Vol 38 (3) ◽  
pp. 412-416 ◽  
Author(s):  
Nicola A. Lewis ◽  
Marc A. Levitt ◽  
Garret S. Zallen ◽  
Mona S. Zafar ◽  
Karen L. Iacono ◽  
...  
Keyword(s):  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Rectal Biopsy ◽  
Biopsy Result

scholarly journals Hirschsprung’s Disease: Diagnosis and Management

2021 ◽  
Vol 10 (2) ◽  
pp. 104-113
Author(s):  
Md Benzamin ◽  
Md Rukunuzzaman ◽  
Md Wahiduzzaman Mazumder ◽  
ASM Bazlul Karim
Keyword(s):  
Hirschsprung's Disease ◽  
Hirschsprung’S Disease ◽  
Rectal Biopsy ◽  
Disease Diagnosis ◽  
Radiological Investigation ◽  
Functional Intestinal Obstruction ◽  
The Common ◽  
High Index Of Suspicion ◽  
Hirschprung's Disease ◽  
Related Mortality

Hirschsprung’s disease (HD) is a rare genetic congenital defect of intestine causing failure of migration of parasympathetic ganglionic cells in some definite part of intestine, resulting in functional intestinal obstruction. It commonly involves rectosigmoid region of colon but other parts of colon or total colon, even small intestine may be affected. Incidence is 1/5000 live births. It is one of the common pediatric surgical problems and 2nd most organic cause of constipation. Symptoms may be evident from 1st day of life. About 90% infants with Hirschprung’s disease fail to pass meconium in 1st 24 hours of life. About 80% HD cases are diagnosed in early few months of life and present with abdominal distention, constipation, poor feeding, vomiting etc. HD enterocolitis is a devastating condition related to mortality. HD may be associated with some congenital anomalies and syndrome. High index of suspicion is the main key to diagnosis. Radiological investigation supports the diagnosis and rectal biopsy for histopathology is confirmatory. Although it is a surgical problem, physician can play a key role in early diagnosis and thus help to prevent HD enterocolitis-related mortality and restore near-normal life. J Enam Med Col 2020; 10(2): 104-113

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