One-stage repair of anorectal malformations in females with vestibular fistula: a systematic review and meta-analysis

ObjectiveTo identify observational studies which used data from more than one primary care electronic health record (EHR) database, and summarise key characteristics including: objective and rationale for using multiple data sources; methods used to manage, analyse and (where applicable) combine data; and approaches used to assess and report heterogeneity between data sources.DesignA systematic review of published studies.Data sourcesPubmed and Embase databases were searched using list of named primary care EHR databases; supplementary hand searches of reference list of studies were retained after initial screening.Study selectionObservational studies published between January 2000 and May 2018 were selected, which included at least two different primary care EHR databases.Results6054 studies were identified from database and hand searches, and 109 were included in the final review, the majority published between 2014 and 2018. Included studies used 38 different primary care EHR data sources. Forty-seven studies (44%) were descriptive or methodological. Of 62 analytical studies, 22 (36%) presented separate results from each database, with no attempt to combine them; 29 (48%) combined individual patient data in a one-stage meta-analysis and 21 (34%) combined estimates from each database using two-stage meta-analysis. Discussion and exploration of heterogeneity was inconsistent across studies.ConclusionsComparing patterns and trends in different populations, or in different primary care EHR databases from the same populations, is important and a common objective for multi-database studies. When combining results from several databases using meta-analysis, provision of separate results from each database is helpful for interpretation. We found that these were often missing, particularly for studies using one-stage approaches, which also often lacked details of any statistical adjustment for heterogeneity and/or clustering. For two-stage meta-analysis, a clear rationale should be provided for choice of fixed effect and/or random effects or other models.

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One-stage urethroplasty for lichen sclerosus related urethral stricture disease: A meta-analysis and systematic review

European Urology ◽

10.1016/s0302-2838(21)00777-6 ◽

2021 ◽

Vol 79 ◽

pp. S556

Author(s):

J. Kurtzman ◽

R. Blum ◽

S. Brandes

Keyword(s):

Systematic Review ◽

Urethral Stricture ◽

Meta Analysis ◽

Lichen Sclerosus ◽

Urethral Stricture Disease ◽

One Stage

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SINGLE-STAGE PROCEDURES FOR ANORECTAL MALFORMATIONS: A SYSTEMATIC REVIEW AND META-ANALYSIS

Journal of Pediatric Surgery ◽

10.1016/j.jpedsurg.2021.12.024 ◽

2022 ◽

Author(s):

Leila Hartford ◽

Giulia Brisighelli ◽

Tarryn Gabler ◽

Chris Westgarth-Taylor

Keyword(s):

Systematic Review ◽

Meta Analysis ◽

Anorectal Malformations ◽

Single Stage

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Short and long-term quality of life outcomes in children after surgery for Hirschsprung Disease or Anorectal Malformations: A systematic review and meta-analysis

10.31219/osf.io/zqbgx ◽

2020 ◽

Author(s):

Irina Oltean ◽

Emily Beveridge ◽

Lamia Hayawi ◽

Vid Bijelic ◽

Ahmed Nasr

Keyword(s):

Quality Of Life ◽

Systematic Review ◽

Psychosocial Functioning ◽

Meta Analysis ◽

Hirschsprung Disease ◽

Cochrane Collaboration ◽

Anorectal Malformations ◽

Case Control Studies ◽

Social And Emotional

There is paucity of evidence examining quality of life in children with HD and ARM prioritizing dimensions other than physical functioning, such as psychosocial functioning in a precise manner. As such, we have developed a systematic review protocol to narratively and quantitatively summarize the physical and psychosocial functioning of children affected by HD and ARM in hopes of addressing this limitation. The following databases were searched on Nov 5, 2019: MEDLINE including Epub Ahead of Print, In-Process & Other Non-Indexed Citations (1946 to October 25, 2019) and Embase (1947 to 2019 October 25) and the CENTRAL Trials Registry of the Cochrane Collaboration (September 2019 Issue) using the Ovid interface. Searches were limited to English, to journal articles, and articles published since 2006. This review will identify retrospective and prospective cohort studies, case-control studies, case studies with greater than 5 participants, and randomized-control trials where the quality of life (i.e., physical and/or social functioning) of children aged 0-18 years with either anorectal malformations or Hirschprung’s disease is reported by children or parent proxies. Understanding the quality of life of children affected by HD and ARM after surgery will help clinical practitioners, specifically surgeons, create tailored and comprehensive protocols for managing these diseases while recognising the physical, social, and emotional toll they can inflict on children.

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