scholarly journals Beitragsserie zur Ross-Operation

2021 ◽  
Vol 35 (6) ◽  
pp. 320-321
Author(s):  
Martin Misfeld
Keyword(s):  
2010 ◽  
Vol 58 (S 01) ◽  
Author(s):  
S Subramanian ◽  
G Pettersson ◽  
L Svensson
Keyword(s):  

2007 ◽  
Vol 55 (S 1) ◽  
Author(s):  
PM Dohmen ◽  
D Gabbieri ◽  
S Dushe ◽  
A Lembcke ◽  
S Holinski ◽  
...  
Keyword(s):  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Shaohua Wu ◽  
Vikas Kumar ◽  
Peng Xiao ◽  
Mitchell Kuss ◽  
Jung Yul Lim ◽  
...  

AbstractHeart valve disease is a common manifestation of cardiovascular disease and is a significant cause of cardiovascular morbidity and mortality worldwide. The pulmonary valve (PV) is of primary concern because of its involvement in common congenital heart defects, and the PV is usually the site for prosthetic replacement following a Ross operation. Although effects of age on valve matrix components and mechanical properties for aortic and mitral valves have been studied, very little is known about the age-related alterations that occur in the PV. In this study, we isolated PV leaflets from porcine hearts in different age groups (~ 4–6 months, denoted as young versus ~ 2 years, denoted as adult) and studied the effects of age on PV leaflet thickness, extracellular matrix components, and mechanical properties. We also conducted proteomics and RNA sequencing to investigate the global changes of PV leaflets and passage zero PV interstitial cells in their protein and gene levels. We found that the size, thickness, elastic modulus, and ultimate stress in both the radial and circumferential directions and the collagen of PV leaflets increased from young to adult age, while the ultimate strain and amount of glycosaminoglycans decreased when age increased. Young and adult PV had both similar and distinct protein and gene expression patterns that are related to their inherent physiological properties. These findings are important for us to better understand the physiological microenvironments of PV leaflet and valve cells for correctively engineering age-specific heart valve tissues.


Author(s):  
Alessandro Varrica ◽  
Angela Satriano ◽  
Alessandro Frigiola ◽  
Alessandro Giamberti
Keyword(s):  

2010 ◽  
Vol 139 (6) ◽  
pp. 1420-1423 ◽  
Author(s):  
Francis Juthier ◽  
Carlo Banfi ◽  
André Vincentelli ◽  
Pierre-Vladimir Ennezat ◽  
Thierry Le Tourneau ◽  
...  

2005 ◽  
Vol 13 (4) ◽  
pp. 321-324 ◽  
Author(s):  
Taweesak Chotivatanapong ◽  
Choosak Kasemsarn ◽  
Chaiwuth Yosthasurodom ◽  
Pradistchai Chaiseri ◽  
Vibhan Sungkahapong ◽  
...  

The feasibility and function of autologous pericardial valved conduit for right ventricular outflow tract reconstruction in the Ross operation were assessed. Between June 1997 and April 2002, 31 patients underwent this procedure at our institution; one was lost to follow-up. The other 26 males and 4 females were aged 17 to 60 years (mean, 36.6 years). Causes of aortic valve disease were infective endocarditis in 26 and rheumatic valve disease in 4. Mean follow-up was 16.7 months (range, 1–58 months). Preoperatively, 9 patients were in functional class II, 19 in class III, and 2 in class IV. Concomitant procedures included coronary artery bypass (1), mitral valve replacement (6), tricuspid valve replacement (1), and ventricular septal defect closure (1). Mean aortic crossclamp time was 199.4 min. There were 4 (13.3%) hospital deaths and no late death. Mean postoperative functional class was 1.17 with +0.36 aortic regurgitation, a peak gradient of 21.9 mm Hg (range, 6–59 mm Hg) across the conduit, and grade +0.96 pulmonary regurgitation. No conduit-related complication was detected. Use of autologous valved conduit for the Ross operation is feasible. Long-term follow-up is mandatory to assess durability.


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