Postnatal development of the reproductive system in the grey short-tailed opossum, Monodelphis domestica

2004 ◽  
Vol 208 (2) ◽  
pp. 121-133 ◽  
Author(s):  
S. Mackay ◽  
Q. Xie ◽  
S. L. Ullmann ◽  
D. P. Gilmore ◽  
A. P. Payne
Keyword(s):  
Postnatal Development ◽  
Reproductive System ◽  
Monodelphis Domestica

scholarly journals Postnatal Development of Leydig Cells in the Opossum (Monodelphis domestica): An Immunocytochemical and Endocrinological Study1

1998 ◽  
Vol 58 (3) ◽  
pp. 664-669 ◽  
Author(s):  
Q. Xie ◽  
S. Mackay ◽  
S. L. Ullmann ◽  
D. P. Gilmore ◽  
A. P. Payne ◽  
...  
Keyword(s):  
Postnatal Development ◽  
Leydig Cells ◽  
Monodelphis Domestica

scholarly journals Impact of Age on the Male Reproductive System from the Pathologist’s Perspective

2016 ◽  
Vol 45 (1) ◽  
pp. 195-205 ◽  
Author(s):  
Catherine A. Picut ◽  
Amera K. Remick
Keyword(s):  
Postnatal Development ◽  
Reproductive System ◽  
Reproductive Organs ◽  
Male Reproductive System ◽  
Laboratory Animals ◽  
Large Animal ◽  
Age Related ◽  
Organ Systems ◽  
Microscopic Evaluation ◽  
Tissue Changes

Age, and in particular young age, can significantly impact the response to toxicants in animals and can greatly influence the interpretation of tissue changes by the toxicologic pathologist. Although this applies to multiple organ systems, the current review focuses on the male reproductive system. When performing microscopic evaluation of male reproductive organs, the toxicologic pathologist must be aware of the dynamic changes in histomorphology, predominantly driven by timed hormonal alterations, at various life stages. Specific challenges pathologists face are understanding the appearance of male reproductive tissues throughout the neonatal, infantile, and juvenile developmental periods, recognizing when normal looks abnormal during tissue development, defining sexual maturity, and working with high interanimal variability in maturation rate and histologic appearance in developing large laboratory animals, such as nonhuman primates, dogs, and pigs. This review describes postnatal development of the male reproductive system in the rat, demonstrates how assessing toxicity during a defined window of postnatal development in the rat may improve definition of toxicant timing and targets, and discusses challenges associated with the interpretation of toxicity in immature large animal species. The emphasis is on key age-related characteristics that influence the interpretation of tissue changes by the toxicologic pathologist.

Species Comparison of Postnatal Development of the Female Reproductive System

2017 ◽  
Vol 110 (3) ◽  
pp. 163-189 ◽  
Author(s):  
Susan B. Laffan ◽  
Lorraine M. Posobiec ◽  
Jenny E. Uhl ◽  
Justin D. Vidal
Keyword(s):  
Postnatal Development ◽  
Reproductive System ◽  
Female Reproductive System ◽  
Species Comparison
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