Histone deacetylase inhibitor ITF2357 (givinostat) reverts transformed phenotype and counteracts stemness in in vitro and in vivo models of human glioblastoma

2018 ◽  
Vol 145 (2) ◽  
pp. 393-409 ◽  
Author(s):  
Francesco Marampon ◽  
Flavio Leoni ◽  
Andrea Mancini ◽  
Ilaria Pietrantoni ◽  
Silvia Codenotti ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
In Vivo Models ◽  
Human Glioblastoma ◽  
Deacetylase Inhibitor

Histone deacetylase inhibitor, FK228, induces apoptosis and suppresses cell proliferation of human glioblastoma cells in vitro and in vivo

2004 ◽  
Vol 107 (6) ◽  
pp. 523-531 ◽  
Author(s):  
Hiroki Sawa ◽  
Hiromi Murakami ◽  
Masaoki Kumagai ◽  
Matsuyoshi Nakasato ◽  
Shigeru Yamauchi ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Glioblastoma Cells ◽  
Human Glioblastoma ◽  
Deacetylase Inhibitor ◽  
Human Glioblastoma Cells

CRA-026440: a potent, broad-spectrum, hydroxamic histone deacetylase inhibitor with antiproliferative and antiangiogenic activity in vitro and in vivo

2006 ◽  
Vol 5 (7) ◽  
pp. 1693-1701 ◽  
Author(s):  
Z. Alexander Cao ◽  
Kathryn E. Bass ◽  
Sriram Balasubramanian ◽  
Liang Liu ◽  
Brian Schultz ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Broad Spectrum ◽  
Histone Deacetylase Inhibitor ◽  
Antiangiogenic Activity ◽  
Deacetylase Inhibitor

Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo

2012 ◽  
Vol 56 (1) ◽  
pp. 176-183 ◽  
Author(s):  
Huanjie Shao ◽  
Chun Gao ◽  
Haikuo Tang ◽  
Hao Zhang ◽  
Lewis R. Roberts ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Dual Targeting ◽  
Deacetylase Inhibitor

Effects of FK228, a novel histone deacetylase inhibitor, on human lymphoma U-937 cells in vitro and in vivo

2002 ◽  
Vol 64 (7) ◽  
pp. 1079-1090 ◽  
Author(s):  
Yuka Sasakawa ◽  
Yoshinori Naoe ◽  
Takeshi Inoue ◽  
Tatsuya Sasakawa ◽  
Masahiko Matsuo ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Deacetylase Inhibitor ◽  
Human Lymphoma

scholarly journals Histone deacetylase inhibitor MPT0B291 suppresses Glioma Growth in vitro and in vivo partially through acetylation of p53

2020 ◽  
Vol 16 (16) ◽  
pp. 3184-3199
Author(s):  
Batsaikhan Buyandelger ◽  
Eli E Bar ◽  
Kuo-Sheng Hung ◽  
Ruei-Ming Chen ◽  
Yung-Hsiao Chiang ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Deacetylase Inhibitor ◽  
Glioma Growth

scholarly journals Histone deacetylase inhibitor NVP-LAQ824 has significant activity against myeloid leukemia cells in vitro and in vivo

Leukemia ◽  
2004 ◽  
Vol 18 (12) ◽  
pp. 1951-1963 ◽  
Author(s):  
E Weisberg ◽  
L Catley ◽  
J Kujawa ◽  
P Atadja ◽  
S Remiszewski ◽  
...  
Keyword(s):  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Myeloid Leukemia ◽  
Leukemia Cells ◽  
Significant Activity ◽  
Deacetylase Inhibitor

Phosphodiesterase inhibitor, pentoxifylline enhances anticancer activity of histone deacetylase inhibitor, MS-275 in human breast cancer in vitro and in vivo

2015 ◽  
Vol 764 ◽  
pp. 508-519 ◽  
Author(s):  
Saranya Nidhyanandan ◽  
Thippeswamy S. Boreddy ◽  
Kothapalli B. Chandrasekhar ◽  
Neetinkumar D. Reddy ◽  
Nagaraj M. Kulkarni ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Anticancer Activity ◽  
Histone Deacetylase ◽  
Histone Deacetylase Inhibitor ◽  
Human Breast Cancer ◽  
Phosphodiesterase Inhibitor ◽  
Human Breast ◽  
Deacetylase Inhibitor

scholarly journals MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo

2008 ◽  
Vol 7 (4) ◽  
pp. 759-768 ◽  
Author(s):  
Marielle Fournel ◽  
Claire Bonfils ◽  
Yu Hou ◽  
Pu Theresa Yan ◽  
Marie-Claude Trachy-Bourget ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Histone Deacetylase ◽  
Broad Spectrum ◽  
Histone Deacetylase Inhibitor ◽  
Deacetylase Inhibitor
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