Comprehensive clinical approach to renal tubular acidosis

2015 ◽  
Vol 19 (4) ◽  
pp. 556-561 ◽  
Author(s):  
Sonia Sharma ◽  
Ankur Gupta ◽  
Sanjiv Saxena
Keyword(s):  
Renal Tubular Acidosis ◽  
Clinical Approach ◽  
Renal Tubular

scholarly journals A physiology-based approach to a patient with hyperkalemic renal tubular acidosis

2018 ◽  
Vol 40 (4) ◽  
pp. 410-417 ◽  
Author(s):  
Juliana Menegussi ◽  
Luiza Sarmento Tatagiba ◽  
Júlia Guasti P. Vianna ◽  
Antonio Carlos Seguro ◽  
Weverton Machado Luchi
Keyword(s):  
Renal Tubular Acidosis ◽  
Transplant Patient ◽  
Fractional Excretion ◽  
Plasma Potassium ◽  
Clinical Approach ◽  
Systemic Fungal Infection ◽  
Plasma Potassium Level ◽  
Recent Diagnosis ◽  
Renal Tubular

ABSTRACT Hyperkalemic renal tubular acidosis is a non-anion gap metabolic acidosis that invariably indicates an abnormality in potassium, ammonium, and hydrogen ion secretion. In clinical practice, it is usually attributed to real or apparent hypoaldosteronism caused by diseases or drug toxicity. We describe a 54-year-old liver transplant patient that was admitted with flaccid muscle weakness associated with plasma potassium level of 9.25 mEq/L. Additional investigation revealed type 4 renal tubular acidosis and marked hypomagnesemia with high fractional excretion of magnesium. Relevant past medical history included a recent diagnosis of Paracoccidioidomycosis, a systemic fungal infection that is endemic in some parts of South America, and his outpatient medications contained trimethoprim-sulfamethoxazole, tacrolimus, and propranolol. In the present acid-base and electrolyte case study, we discuss a clinical approach for the diagnosis of hyperkalemic renal tubular acidosis and review the pathophysiology of this disorder.

scholarly journals Clinical approach to renal tubular acidosis in children

2021 ◽  
Vol 35 ◽  
pp. 88-94
Author(s):  
Soumya Reddy ◽  
Nivedita Kamath
Keyword(s):  
Metabolic Disease ◽  
Metabolic Acidosis ◽  
Renal Tubular Acidosis ◽  
Fanconi Syndrome ◽  
Specific Treatment ◽  
Supportive Therapy ◽  
Distal Tubule ◽  
Clinical Approach ◽  
Hyperchloremic Metabolic Acidosis ◽  
Renal Tubular

Renal tubular acidosis (RTA) is a common inherited tubulopathy in children. Proximal RTA, usually secondary to a systemic metabolic disease, is characterized by a generalized dysfunction of the proximal tubule resulting in Fanconi syndrome. Distal RTA occurs due to mutation in the transporters of the distal tubule resulting in acidification defects. Hyperchloremic metabolic acidosis with normal anion gap is the characteristic feature of RTA. In addition to supportive therapy, specific treatment for the underlying etiology and regular monitoring of growth and laboratory parameters are of utmost importance.

Renal tubular acidosis

1968 ◽  
Vol 121 (1) ◽  
pp. 81-86 ◽  
Author(s):  
W. M. Bennett
Keyword(s):  
Renal Tubular Acidosis ◽  
Renal Tubular

A Novel Mutation in the Anion Exchanger 1 Gene Is Associated With Familial Distal Renal Tubular Acidosis and Nephrocalcinosis

PEDIATRICS ◽  
2003 ◽  
Vol 112 (6) ◽  
pp. 1361-1367 ◽  
Author(s):  
L. Cheidde ◽  
T. C. Vieira ◽  
P. R. M. Lima ◽  
S. T. O. Saad ◽  
I. P. Heilberg
Keyword(s):  
Renal Tubular Acidosis ◽  
Anion Exchanger ◽  
Novel Mutation ◽  
Distal Renal Tubular Acidosis ◽  
Anion Exchanger 1 ◽  
Renal Tubular
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