A retrospective study of the risk factors and the prognosis in patients with papillary thyroid carcinoma depending on the number of lymph node metastasis

2021 ◽  
Author(s):  
Zhong Ying Rui ◽  
Yang Liu ◽  
Wei Zheng ◽  
Xuan Wang ◽  
Zhao Wei Meng ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lymph Node ◽  
Retrospective Study ◽  
Papillary Thyroid Carcinoma ◽  
Lymph Node Metastasis ◽  
Thyroid Carcinoma ◽  
Papillary Thyroid ◽  
Node Metastasis

scholarly journals Risk Factors for Contralateral Occult Carcinoma in Patients With Unilateral Papillary Thyroid Carcinoma: A Retrospective Study and Meta-Analysis

2021 ◽  
Vol 12 ◽  
Author(s):  
Fan Zhang ◽  
Boyuan Zheng ◽  
Xiaohui Yu ◽  
Xichang Wang ◽  
Shiwei Wang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Lymph Node ◽  
Retrospective Study ◽  
Papillary Thyroid Carcinoma ◽  
Lymph Node Metastasis ◽  
Thyroid Carcinoma ◽  
Meta Analysis ◽  
Benign Nodule ◽  
Papillary Thyroid ◽  
Node Metastasis

BackgroundBilateral lesions are common in papillary thyroid carcinoma (PTC). For patients with unilateral PTC, occult carcinoma that is not detected preoperatively, but pathologically after surgery, might remain in the contralateral lobe. In this situation, inadequate surgical extent could cause relapse and even lead to re-operation. Here, we explore the frequency and investigate the risk factors of contralateral occult PTC in unilateral PTC through a retrospective study conducted by our team and published articles online, respectively.MethodsWe collected the patients’ clinical data in our hospital, whose cancer was determined to be confined to the unilateral lobe by preoperative image examination (N = 204). These patients underwent initially total or near-total thyroidectomy and included their clinical data in the meta-analysis. We searched related literature in the PubMed, Embase, MEDLINE, Cochrane, and Web of Science databases until December 7, 2020, in order to perform a meta-analysis. The relevant articles were examined and the eligible studies were included to assess the association between clinicopathologic factors and contralateral occult PTC.ResultsThe meta-analysis included nine studies (involving 4347 patients). Of these, eight studies were from the databases, and one study was our retrospective data. The meta-analysis showed that the prevalence of contralateral occult PTC was 26.6% in all patients. A tumor size > 1 cm, ipsilateral multifocality, contralateral benign nodule, and central lymph node metastasis were significantly associated with contralateral occult PTC. In contrast, sex, age, ETE, capsular invasion, BRAF mutation, Hashimoto thyroiditis, and lateral lymph node metastasis were insignificantly associated with contralateral occult PTC.ConclusionThe meta-analysis identified a tumor size > 1 cm, ipsilateral multifocality, contralateral benign nodule, and CLNM as being significant risk factors for contralateral occult PTC. These findings may guide the extent of surgery in unilateral PTC patients.

Risk factors for persistent disease in papillary thyroid carcinoma with lymph node metastasis

2016 ◽  
Vol 37 (7) ◽  
pp. 721-726
Author(s):  
Aylin Oral ◽  
Bulent Yazici ◽  
Aysegül Akgün ◽  
Hür Hassoy ◽  
Zehra Özcan
Keyword(s):  
Risk Factors ◽  
Lymph Node ◽  
Papillary Thyroid Carcinoma ◽  
Lymph Node Metastasis ◽  
Thyroid Carcinoma ◽  
Papillary Thyroid ◽  
Persistent Disease ◽  
Node Metastasis
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