scholarly journals Titrating droxidopa to maximize symptomatic benefit in a patient with Parkinson disease and neurogenic orthostatic hypotension

2017 ◽  
Vol 27 (S1) ◽  
pp. 15-16 ◽  
Author(s):  
Fiona Gupta ◽  
Beverly Karabin ◽  
Ali Mehdirad
Keyword(s):  
Parkinson Disease ◽  
Orthostatic Hypotension ◽  
Neurogenic Orthostatic Hypotension ◽  
Symptomatic Benefit

scholarly journals Adjusting droxidopa for neurogenic orthostatic hypotension in a patient with Parkinson disease

2017 ◽  
Vol 27 (S1) ◽  
pp. 17-19 ◽  
Author(s):  
Brent P. Goodman ◽  
Daniel Claassen ◽  
Ali Mehdirad
Keyword(s):  
Parkinson Disease ◽  
Orthostatic Hypotension ◽  
Neurogenic Orthostatic Hypotension

Neurogenic orthostatic hypotension as the initial feature of Parkinson disease

2012 ◽  
Vol 22 (4) ◽  
pp. 203-206 ◽  
Author(s):  
Valeria Milazzo ◽  
Cristina Di Stefano ◽  
Serena Servo ◽  
Maurizio Zibetti ◽  
Leonardo Lopiano ◽  
...  
Keyword(s):  
Parkinson Disease ◽  
Orthostatic Hypotension ◽  
Neurogenic Orthostatic Hypotension

Abstract P381: Understanding the Symptoms of Neurogenic Orthostatic Hypotension: Results From a Survey of Patients and Caregivers

Hypertension ◽  
2017 ◽  
Vol 70 (suppl_1) ◽  
Author(s):  
Lawrence A Hewitt ◽  
Charles H Adler ◽  
Daniel O Claassen ◽  
Christopher H Gibbons ◽  
Satish R Raj
Keyword(s):  
Multiple System Atrophy ◽  
Parkinson Disease ◽  
Orthostatic Hypotension ◽  
Autonomic Failure ◽  
Alpha Synuclein ◽  
Pure Autonomic Failure ◽  
Motor Symptoms ◽  
Neurogenic Orthostatic Hypotension ◽  
The Past ◽  
Increased Risk

Objective: To understand the burden and impact of symptoms of neurogenic orthostatic hypotension (nOH) on patients Background: nOH and its symptoms such as dizziness/lightheadedness are common in patients with Parkinson disease (PD) and other forms of autonomic dysfunction. Methods: An author-designed, US-based survey was conducted by Harris Poll. Eligible participants were aged ≥18 years with PD, multiple system atrophy (MSA), or pure autonomic failure and ≥1 of the following: orthostatic hypotension, nOH, low BP, OH/nOH symptoms, or were caregivers of eligible patients. Results: Most patients (90%) had a diagnosis of PD, and most caregivers (88%) cared for a patient with PD (Table 1) . Patients (34%) and caregivers (49%) reported experiencing nOH symptoms before PD or MSA motor symptoms and >40% indicated that nOH symptoms were more troublesome than motor manifestations of PD or MSA. Less than a quarter (22%) of respondents suggested symptoms were most severe in the morning; more (30%) reported a consistent severity throughout the day. Patients (40%) and caregivers (63%) reported trouble managing symptoms during the day. In the past 12 months, a fall due to nOH symptoms was reported by 57% of patients and 80% of caregivers. Conclusions: These findings suggest that nOH symptoms may predate the onset of motor symptoms in neurodegenerative conditions linked to alpha-synuclein pathology. Many respondents report nOH symptoms are the same severity through the day. Patients with nOH may have trouble managing symptoms and note an increased risk for falls.

scholarly journals Neurogenic Orthostatic Hypotension in Parkinson Disease: A Primer

2019 ◽  
Vol 8 (2) ◽  
pp. 307-324 ◽  
Author(s):  
Jeremy K. Cutsforth-Gregory ◽  
Phillip A. Low
Keyword(s):  
Parkinson Disease ◽  
Orthostatic Hypotension ◽  
Neurogenic Orthostatic Hypotension

scholarly journals Droxidopa and Reduced Falls in a Trial of Parkinson Disease Patients With Neurogenic Orthostatic Hypotension

2016 ◽  
Vol 39 (5) ◽  
pp. 220-226 ◽  
Author(s):  
Robert A. Hauser ◽  
Stephane Heritier ◽  
Gerald J. Rowse ◽  
L. Arthur Hewitt ◽  
Stuart H. Isaacson
Keyword(s):  
Parkinson Disease ◽  
Orthostatic Hypotension ◽  
Neurogenic Orthostatic Hypotension
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