scholarly journals Progression of Abdominal Aortic Aneurysm Towards Rupture: Refining Clinical Risk Assessment Using a Fully Coupled Fluid–Structure Interaction Method

2014 ◽  
Vol 43 (1) ◽  
pp. 139-153 ◽  
Author(s):  
Michalis Xenos ◽  
Nicos Labropoulos ◽  
Suraj Rambhia ◽  
Yared Alemu ◽  
Shmuel Einav ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Fluid Structure Interaction ◽  
Interaction Method ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Abdominal Aortic ◽  
Clinical Risk Assessment ◽  
Fully Coupled

Fully Coupled vs. Partially Coupled Fluid-Structure Interaction Methods for Patient-Specific Abdominal Aortic Aneurysm Biomechanics

2007 ◽  
Author(s):  
Christine M. Scotti ◽  
Ender A. Finol
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Fluid Structure Interaction ◽  
Wall Stress ◽  
Patient Specific ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Abdominal Aortic ◽  
Mechanical Factors ◽  
Fully Coupled

Primary among the mechanical factors linked with abdominal aortic aneurysm (AAA) rupture is peak wall stress, frequently quantified as either the maximum principal or Von Mises stress exerted along the diseased arterial wall. Intraluminal pressure, as an impinging normal force on the wall, has been hypothesized as the dominant influence on this stress and thus the majority of numerical modeling studies of AAA mechanics have focused on static computational solid stress (CSS) predictions [1,2]. Unfortunately, retrospective studies comparing the magnitude of wall stress with the failure strength of the aneurysmal wall have yet to consistently predict the outcome for patient-specific AAAs [3,4]. Previous studies have shown that hemodynamics also plays a significant role in both the biological and mechanical factors that exist within AAAs. In the present investigation, partially and fully coupled fluid-structure interaction (p-FSI and f-FSI, respectively) computations of patient-specific AAA models are presented and compared to identify the effect of fluid flow in the biomechanical environment of these aneurysms.

Patient-Based Abdominal Aortic Aneurysm Rupture Risk Prediction with Fluid Structure Interaction Modeling

2010 ◽  
Vol 38 (11) ◽  
pp. 3323-3337 ◽  
Author(s):  
Michalis Xenos ◽  
Suraj H. Rambhia ◽  
Yared Alemu ◽  
Shmuel Einav ◽  
Nicos Labropoulos ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Risk Prediction ◽  
Fluid Structure Interaction ◽  
Aneurysm Rupture ◽  
Rupture Risk ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Abdominal Aortic ◽  
Interaction Modeling

A Fluid Structure Interaction Approach for Patient Based Abdominal Aortic Aneurysm Rupture Risk Prediction

2010 ◽  
Author(s):  
Michalis Xenos ◽  
Suraj Rambhia ◽  
Yared Alemu ◽  
Shmuel Einav ◽  
John J. Ricotta ◽  
...  
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Fluid Structure Interaction ◽  
Patient Specific ◽  
Rupture Risk ◽  
Material Models ◽  
Fluid Structure ◽  
Structure Interaction ◽  
Abdominal Aortic ◽  
Risk Of Rupture

Fluid structure interaction (FSI) simulations of patient-specific fusiform non-ruptured and contained ruptured Abdominal Aortic Aneurysm (AAA) geometries were conducted. The goals were: (1) to test the ability of our FSI methodology to predict the location of rupture, by correlating the high wall stress regions with the rupture location, (2) estimate the state of the pathological condition by calculating the ruptured potential index (RPI) of the AAA and (3) predict the disease progression by comparing healthy and pathological aortas. The patient specific AAA FSI simulations were carried out with advanced constitutive material models of the various components of AAA, including models that describe wall anisotropy based on collagen fibers orientation within the arterial wall, structural strength of the aorta, intraluminal thrombus (ILT), and embedded calcifications. The anisotropic material model used to describe the wall properties closely correlated with experimental results of AAA specimens. The results demonstrate that the anisotropic wall simulations showed higher peak wall stresses as compared to isotropic material models, indicating that the latter may underestimate the AAA risk of rupture. The ILT appeared to provide a cushioning effect reducing the stresses, while small calcifications (small-Ca) appeared to weaken the wall and contribute to the rupture risk. FSI simulations with ruptured AAA demonstrated that the location of the maximal wall stresses and RPI overlap the actual rupture region.

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