Administration of Dopamine to Rats Disorganizes the Rhythm of Protein Synthesis in Hepatocytes

2014 ◽  
Vol 157 (2) ◽  
pp. 220-223 ◽  
Author(s):  
V. Ya. Brodskii ◽  
L. A. Mal’chenko ◽  
T. K. Dubovaya ◽  
D. S. Konchenko ◽  
N. D. Zvezdina
Keyword(s):  
Protein Synthesis ◽  
Rhythm Of Protein Synthesis

Cooperation of Hepatocytes in vitro in the Rhythm of Protein Synthesis is Promoted by the GM1 Ganglioside Contained in Vesicles and Liposomes

2003 ◽  
Vol 30 (6) ◽  
pp. 540-546 ◽  
Author(s):  
V. Ya. Brodsky ◽  
N. V. Nechaeva ◽  
N. D. Zvezdina ◽  
T. E. Novikova ◽  
I. G. Gvazava ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Gm1 Ganglioside ◽  
Rhythm Of Protein Synthesis

Discovery of an hourly rhythm of protein synthesis in human gastric biopsy material

1984 ◽  
Vol 97 (5) ◽  
pp. 666-669
Author(s):  
V. Ya. Brodskii ◽  
S. I. Rapoport ◽  
V. I. Fateeva ◽  
N. V. Nechaeva ◽  
L. V. Kharayan ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Gastric Biopsy ◽  
Biopsy Material ◽  
Rhythm Of Protein Synthesis

Absence of a circadian rhythm of protein synthesis in the rat suprachiasmatic nucleus

1987 ◽  
Vol 76 (1) ◽  
pp. 113-118 ◽  
Author(s):  
Steven F. Glotzbach ◽  
Teri L. Randall ◽  
Carolyn M. Radeke ◽  
H.Craig Heller
Keyword(s):  
Protein Synthesis ◽  
Circadian Rhythm ◽  
Suprachiasmatic Nucleus ◽  
Rhythm Of Protein Synthesis

Mesenchymal stromal cells synchronize the rhythm of protein synthesis under the effect of an exogenous signal

2012 ◽  
Vol 43 (3) ◽  
pp. 196-198
Author(s):  
V. Ya. Brodsky ◽  
A. V. Vasil’ev ◽  
V. V. Terskikh ◽  
N. D. Zvezdina ◽  
V. I. Fateeva ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Mesenchymal Stromal Cells ◽  
Stromal Cells ◽  
Rhythm Of Protein Synthesis

Possible role of ornithine decarboxylase in control of the circahoralian rhythm of protein synthesis

1984 ◽  
Vol 97 (2) ◽  
pp. 176-178 ◽  
Author(s):  
N. V. Nechaeva ◽  
V. I. Fateeva ◽  
K. N. Yarygin ◽  
V. Ya. Brodskii
Keyword(s):  
Protein Synthesis ◽  
Ornithine Decarboxylase ◽  
Rhythm Of Protein Synthesis

scholarly journals The rhythm of protein synthesis does not depend on oscillations of ATP level

1992 ◽  
Vol 103 (2) ◽  
pp. 363-370
Author(s):  
V.Y. Brodsky ◽  
P.Y. Boikov ◽  
N.V. Nechaeva ◽  
Y.G. Yurovitsky ◽  
T.E. Novikova ◽  
...  
Keyword(s):  
Protein Synthesis ◽  
Rat Hepatocytes ◽  
Incorporation Rate ◽  
Synthesis Rate ◽  
Protein Synthesis Rate ◽  
Leucine Incorporation ◽  
Free System ◽  
Atp Level ◽  
Rhythm Of Protein Synthesis ◽  
A Cell

A rhythm of the [3H]leucine incorporation rate with a period of about one hour (circahoralian rhythm) has been found in rat hepatocytes grown in vitro as a monolayer and in liver organ culture. The periodicity of the incorporation rate remained after correction for changes in leucine pool size. A similar periodicity of the leucine incorporation rate was detected in a cell-free system prepared from rat hepatocytes. We have also found circahoralian oscillations of the ATP level and similar oscillations of the leucine tRNA aminoacylation rate in a hepatocyte monolayer. The addition of 1 mM ADP to the culture resulted in a considerable increase in the ATP level in the cells, but the rhythm of protein synthesis was retained under these conditions. The conclusion that there is a flexible association between changes in the ATP and GTP levels on the one hand, and oscillations of the protein synthesis rate on the other, is also supported by experiments with a cell-free system, in which the rhythm of protein synthesis rate was observed in the presence of excess ATP and GTP. We propose an hypothesis to explain the fractal pattern of circahoralian metabolic rhythms.

Melatonin Modifies the Rhythm of Protein Synthesis

2010 ◽  
Vol 149 (1) ◽  
pp. 40-43 ◽  
Author(s):  
V. Y. Brodsky ◽  
N. D. Dubovaya ◽  
T. K. Zvezdina ◽  
V. I. Fateeva ◽  
L. A. Mal’chenko
Keyword(s):  
Protein Synthesis ◽  
Rhythm Of Protein Synthesis
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