scholarly journals Effect of Dapagliflozin on the Functioning of Rat Liver Mitochondria In Vitro

2021 ◽  
Author(s):  
N. V. Belosludtseva ◽  
V. S. Starinets ◽  
K. N. Belosludtsev
Keyword(s):  
Rat Liver ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria

scholarly journals Protein-mediated uptake of vitamin B12 by isolated mitochondria

Blood ◽  
1976 ◽  
Vol 47 (6) ◽  
pp. 923-930 ◽  
Author(s):  
RA Gams ◽  
EM Ryel ◽  
F Ostroy
Keyword(s):  
Vitamin B12 ◽  
Rat Liver ◽  
Mitochondrial Respiration ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria ◽  
Isolated Rat Liver ◽  
Isolated Mitochondria ◽  
Isolated Rat

Abstract Protein-mediated B12 uptake by isolated rat liver mitochondria has been shown to be enhanced by plasma transcobalamin (TC-II) but not by salivary R binder in vitro. The process is enhanced by calcium and depends on active mitochondrial respiration. Following uptake, cyanocobalamin is converted to adenosyl and methylcobalamins and released from the mitochondria. TC-II appears to be required for both cellular and mitochondrial uptake of vitamin B12.

Succinic and Cytochrome Oxidase Activity of Rat Liver Mitochondria After in Vitro Irradiation With Ultraviolet Light

1957 ◽  
Vol 188 (3) ◽  
pp. 547-549 ◽  
Author(s):  
Attilio Canzanelli ◽  
Rhea Sossen ◽  
David Rapport
Keyword(s):  
Cytochrome Oxidase ◽  
Ultraviolet Light ◽  
Rat Liver ◽  
Oxidase Activity ◽  
Biological Effects ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria ◽  
Cytochrome Oxidase Activity ◽  
Order Of Magnitude

Five per cent suspensions of rat liver mitochondria were irradiated with ultraviolet light for varying periods of time and the succinoxidase and cytochrome oxidase activity were determined. Both succinoxidase and cytochrome oxidase activity were reduced by irradiation with ultraviolet. The order of magnitude of the ultraviolet energy necessary to produce such changes is much less than that necessary to produce chemical changes in nucleic acid derivatives, and approaches the amount which has been shown to produce lethal and other biological effects.

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