Cultivation of HEK 293 cell line and production of a member of the superfamily of G-protein coupled receptors for drug discovery applications using a highly efficient novel bioreactor

Hek 293 ◽

Highly Efficient ◽

G Protein Coupled ◽

Hek 293 Cell Line

Orphan G protein-coupled receptors: a neglected opportunity for pioneer drug discovery

Trends in Pharmacological Sciences ◽

10.1016/s0165-6147(97)01117-6 ◽

1997 ◽

Vol 18 (11) ◽

pp. 430-437 ◽

Cited By ~ 74

Author(s):

J Stadel

Keyword(s):

Drug Discovery ◽

G Protein ◽

Recombinant G Protein-Coupled Receptors for Drug Discovery

Drug Discovery Series - G Protein-Coupled Receptors in Drug Discovery ◽

10.1201/9781420028218.ch8 ◽

2005 ◽

pp. 143-158

Author(s):

Kenneth Lundstrom

Keyword(s):

Drug Discovery ◽

G Protein ◽

G-protein coupled receptors: advances in simulation and drug discovery

Current Opinion in Structural Biology ◽

10.1016/j.sbi.2016.06.008 ◽

2016 ◽

Vol 41 ◽

pp. 83-89 ◽

Cited By ~ 50

Author(s):

Yinglong Miao ◽

J Andrew McCammon

Keyword(s):

Drug Discovery ◽

G Protein ◽

G-protein Coupled Receptors: A Potential Candidate for Drug Discovery

International Journal of Pharmacology ◽

10.3923/ijp.2017.846.863 ◽

2017 ◽

Vol 13 (7) ◽

pp. 846-863

Author(s):

Pranveer Singh

Keyword(s):

Drug Discovery ◽

G Protein ◽

Potential Candidate ◽

Importance of protein dynamics in the structure-based drug discovery of class A G protein-coupled receptors (GPCRs)

Current Opinion in Structural Biology ◽

10.1016/j.sbi.2019.03.015 ◽

2019 ◽

Vol 55 ◽

pp. 147-153 ◽

Cited By ~ 12

Author(s):

Yoonji Lee ◽

Raudah Lazim ◽

Stephani Joy Y Macalino ◽

Sun Choi

Keyword(s):

Drug Discovery ◽

Protein Dynamics ◽

G Protein ◽

Class A ◽

The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery

Neuropharmacology ◽

10.1016/j.neuropharm.2010.07.001 ◽

2011 ◽

Vol 60 (1) ◽

pp. 36-44 ◽

Cited By ~ 110

Author(s):

Nathan Robertson ◽

Ali Jazayeri ◽

James Errey ◽

Asma Baig ◽

Edward Hurrell ◽

...

Keyword(s):

Drug Discovery ◽

G Protein ◽

Ubiquitination of G Protein-Coupled Receptors: Functional Implications and Drug Discovery

Molecular Pharmacology ◽

10.1124/mol.112.079418 ◽

2012 ◽

Vol 82 (4) ◽

pp. 563-570 ◽

Cited By ~ 34

Author(s):

Michael R. Dores ◽

JoAnn Trejo

Keyword(s):

Drug Discovery ◽

G Protein ◽

Functional Implications ◽

Strategic Research Institute G-Protein-Coupled Receptors Drug Discovery World Summit

Expert Opinion on Investigational Drugs ◽

10.1517/13543784.13.8.1071 ◽

2004 ◽

Vol 13 (8) ◽

pp. 1071-1074

Author(s):

Christian C Felder

Keyword(s):

Drug Discovery ◽

G Protein ◽

World Summit ◽

Strategic Research ◽

G Protein Coupled ◽

Research Institute

G Protein-Coupled Receptors in Drug Discovery

10.1007/978-1-60327-317-6 ◽

2009 ◽

Cited By ~ 2

Keyword(s):

Drug Discovery ◽

G Protein ◽

Editorial [Hot topic: In Silico Approaches in G Protein-Coupled Receptors (GPCRs) Drug Discovery: Quo Vadis? (Executive Editor: Stefano Moro)]

Current Pharmaceutical Design ◽

10.2174/138161209789824812 ◽

2009 ◽

Vol 15 (35) ◽

pp. 3992-3993

Author(s):

Stefano Moro

Keyword(s):

Drug Discovery ◽

G Protein ◽

In Silico ◽

Executive Editor ◽

Quo Vadis ◽