The paper reports the first attempt at changing cooling treatment of
synthesizing method in order to investigate its effect on the physical
properties of sol-gel derived nano bioactive glass-ceramic in the system
58SiO2-33CaO-9P2O5 (wt.%). We hypothesized that the method of cooling may
affect the properties of nano bioactive glass-ceramic. To test this
hypothesis, two different method of cooling treatment was applied after
calcinations in synthesizing method. Both quenched and unquenched nano
bioactive glass-ceramics were soaked in Ringer?s solution with bovine serum
albumin (BSA) for bioactivity evaluation. The obtained samples were analyzed
for their composition, crystalinity and morphology through X-ray powder
diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), surface
electron microscope (SEM) and transmission electron microscope (TEM). The SEM
images showed that the morphology of nano bioactive glass-ceramics was
completely changed by quenching process. Results of in vitro bioactivity
evaluation revealed that the unquenched attains faster apatite formation
ability than the quenched sample. Other properties of these two
morphologically different nano bioactive glass-ceramics were strongly
discussed.