Coordinated targeting of MMP-2/MMP-9 by miR-296-3p/FOXCUT exerts tumor-suppressing effects in choroidal malignant melanoma

2017 ◽  
Vol 445 (1-2) ◽  
pp. 25-33 ◽  
Author(s):  
Xinhe Wang ◽  
Yuedong Hu ◽  
Jianyi Cui ◽  
Yun Zhou ◽  
Lei Chen
Orbit ◽  
2021 ◽  
pp. 1-2
Author(s):  
Sana Qureshi ◽  
Dane H. Slentz ◽  
Victor M. Elner ◽  
Hakan Demirci

2006 ◽  
pp. 480-489
Author(s):  
IVANA K. KIM ◽  
EVANGELOS S. GRAGOUDAS

The most valuable diagnostic method in intraocular tumors is indirect ophthalmoscopy. USG is very important in determining the thickness of the lesion and documenting post-treatment changes. However, in today's conditions, we have important auxiliary examination opportunities. OCT is especially important in detecting macular edema and fluid. In choroidal melanomas, thickening and edema of the macula may be observed before treatment due to increased VEGF levels in the eye. OCT is important in detecting such changes. Since FAF shows the amount of lipofuscin in the lesion, it reveals the activity of the lesion. Hyperotofluorescence of> 50% of the lesion surface, in other words, the diffuse pattern is a risk factor for growth and metastasis. On fluorescein angiography, choroidal melanoma shows focal hyperfluorescence starting from the late venous phase and gradually increasing.


2012 ◽  
Vol 35 (7) ◽  
pp. 535.e1-535.e4 ◽  
Author(s):  
T. Sakuma ◽  
R. Iseki ◽  
A. Mimura ◽  
N. Tanigawa ◽  
R. Takamizu

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