Approach to the patient in the diagnosis of Choroidal Malignant Melanoma. Question and Answer

2019 ◽  
pp. 317-320
Keyword(s):  
Risk Factor ◽  
Malignant Melanoma ◽  
Diagnostic Method ◽  
Choroidal Melanoma ◽  
Intraocular Tumors ◽  
Indirect Ophthalmoscopy ◽  
Choroidal Malignant Melanoma ◽  
Choroidal Melanomas ◽  
Venous Phase ◽  
Treatment Changes

The most valuable diagnostic method in intraocular tumors is indirect ophthalmoscopy. USG is very important in determining the thickness of the lesion and documenting post-treatment changes. However, in today's conditions, we have important auxiliary examination opportunities. OCT is especially important in detecting macular edema and fluid. In choroidal melanomas, thickening and edema of the macula may be observed before treatment due to increased VEGF levels in the eye. OCT is important in detecting such changes. Since FAF shows the amount of lipofuscin in the lesion, it reveals the activity of the lesion. Hyperotofluorescence of> 50% of the lesion surface, in other words, the diffuse pattern is a risk factor for growth and metastasis. On fluorescein angiography, choroidal melanoma shows focal hyperfluorescence starting from the late venous phase and gradually increasing.

scholarly journals Multifocal Intraretinal Tumour Deposits following Treatment of an Ipsilateral Choroidal Melanoma

2020 ◽  
Vol 6 (6) ◽  
pp. 410-415
Author(s):  
Aaron Jamison ◽  
Julie Connolly ◽  
Paul Cauchi ◽  
Chee Thum ◽  
Vikas Chadha
Keyword(s):  
Visual Acuity ◽  
Malignant Melanoma ◽  
Uveal Melanoma ◽  
Choroidal Melanoma ◽  
Black Spot ◽  
Retrospective Case ◽  
Snellen Visual Acuity ◽  
Choroidal Malignant Melanoma ◽  
A Site ◽  
Plaque Brachytherapy

<b><i>Background/Aims:</i></b> The aim of this study was to report a patient who, following plaque brachytherapy for a choroidal melanoma, developed two separate retinal foci of malignant melanoma in the same eye, and suggest possible mechanisms that might explain such an occurrence. <b><i>Methods:</i></b> We conducted a retrospective case report. <b><i>Results:</i></b> A 79-year-old Caucasian male developed a left inferotemporal choroidal melanoma in 2016 and subsequently underwent ruthenium-106 plaque brachytherapy under the care of the Scottish Ocular Oncology Service. Serial B-scan ultrasonography demonstrated a post-treatment reduction in tumour height to &#x3c;2 mm. In 2018, 27 months after the treatment, the patient complained of a “black spot” in the centre of his left eye vision. His visual acuity had reduced to counting fingers from 6/24 (corrected Snellen visual acuity). Several new areas of pigmentation and elevation were observed, and uveal melanoma recurrence was initially suspected. Given the multifocal nature of the presentation, the multi-disciplinary team recommended enucleation. Histological examination of the enucleated eye revealed three discrete foci of malignant melanoma – the previously treated choroidal malignant melanoma, and two solitary deposits of malignant melanoma within the retina. <b><i>Conclusion:</i></b> Retinoinvasive melanoma is a rare subtype of uveal melanoma, characterised by transvitreal melanoma invasion of the retina at a site non-contiguous with the uveal tumour, which may explain the clinical and pathological findings of the reported case.

Choroidal malignant melanoma masquerading as orbital cellulitis

Orbit ◽  
2021 ◽  
pp. 1-2
Author(s):  
Sana Qureshi ◽  
Dane H. Slentz ◽  
Victor M. Elner ◽  
Hakan Demirci
Keyword(s):  
Malignant Melanoma ◽  
Orbital Cellulitis ◽  
Choroidal Malignant Melanoma

Radiotherapy as a risk factor for malignant melanoma after childhood skin hemangioma

2012 ◽  
Vol 22 (1) ◽  
pp. 77-85 ◽  
Author(s):  
Nadia Haddy ◽  
Abdeddahir Mousannif ◽  
Catherine Paoletti ◽  
Marie-Gabrielle Dondon ◽  
Akhtar Shamsaldin ◽  
...  
Keyword(s):  
Risk Factor ◽  
Malignant Melanoma

scholarly journals Optical Coherence Tomography: An Adjunctive Tool for Differentiating between Choroidal Melanoma and Metastasis

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Vicktoria Vishnevskia-Dai ◽  
Dinah Zur ◽  
Shiran Yaacobi ◽  
Iris Moroz ◽  
Hadas Newman ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Retinal Thickness ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Choroidal Melanoma ◽  
Case Series ◽  
Subretinal Fluid ◽  
Optical Coherence ◽  
Choroidal Melanomas ◽  
Anterior Choroidal

Purpose.To investigate the value of optical coherence tomography (OCT) for differentiation between choroidal melanoma and metastasis based on characteristics of the anterior choroidal surface and the chorioretinal interface.Methods.This retrospective observational case series included 29 patients with untreated choroidal melanomas and 21 patients with untreated choroidal metastases. Regularity and lobularity characteristics of the anterior choroidal surface were evaluated in a masked manner. Retinal and retinal pigment epithelium (RPE) findings were documented as well.Results.OCT demonstrated a regular and smooth anterior choroidal surface in 89.7% of the eyes with melanoma and in 47.6% of the eyes with metastasis (p=0.002; sensitivity = 89.7%; specificity = 52.4%). The anterior choroidal contour was lobulated in 81.0% of the eyes with metastasis versus 17.2% of the eyes with melanoma (p<0.001; sensitivity = 82.8%; specificity = 81.0%). RPE thickness and neuroretinal characteristics (e.g., retinal thickness, the presence of cysts, and the presence of subretinal fluid) were similar in both choroidal tumors.Conclusion. OCT may serve as a noninvasive adjunctive tool for the differential diagnosis of choroidal tumors. Choroidal melanomas usually demonstrate regular surfaces on OCT, while choroidal metastases usually have an irregular and lobulated surface.

Choroidal Malignant Melanoma

2006 ◽  
pp. 480-489
Author(s):  
IVANA K. KIM ◽  
EVANGELOS S. GRAGOUDAS
Keyword(s):  
Malignant Melanoma ◽  
Choroidal Malignant Melanoma
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