scholarly journals From Carbon-11-Labeled Amino Acids to Peptides in Positron Emission Tomography: the Synthesis and Clinical Application

2018 ◽  
Vol 20 (4) ◽  
pp. 510-532 ◽  
Author(s):  
Aleksandra Pekošak ◽  
Ulrike Filp ◽  
Alex J. Poot ◽  
Albert D. Windhorst
Keyword(s):  
Amino Acids ◽  
Positron Emission Tomography ◽  
Clinical Application ◽  
Emission Tomography ◽  
Positron Emission

Biochemical basics of imaging in positron emission tomography in oncology. Part 1

2019 ◽  
pp. 114-130
Author(s):  
A. V. Leontyev ◽  
N. A. Rubtsova ◽  
A. I. Khalimon ◽  
G. F. Khamadeeva ◽  
M. T. Kuliev ◽  
...  
Keyword(s):  
Amino Acids ◽  
Positron Emission Tomography ◽  
Lipid Metabolism ◽  
Clinical Application ◽  
Nuclear Imaging ◽  
Emission Tomography ◽  
Literature Overview ◽  
Positron Emission ◽  
Indications For Use ◽  
Oncological Practice

This article provides a literature overview of biochemical basics and the clinical application of positron emission tomography, one of the most promising technologies of nuclear imaging in oncology. In the first part we discuss the biokinetics of metabolic radiopharmaceuticals, such as 18F-fluorodeoxyglucose, radiolabeled markers of lipid metabolism 11C- and 18F-choline, 11C-acetate, as well as amino acids analogues – 18F-dihydroxyphenylalanine, 11C-methionine, 18F-fluoroe thyltyrosine, 11C-tryptophan, 18F-flucyclovine. This article includes results of scientific researches, that studied radiopharmaceuticals’ effectiveness in oncological practice. The main indications for use, as well as promising scientific developments in this industry are presented.

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