Effect of liver receptor homolog-1 on cell apoptosis and steroid hormone secretion on granulosa cells from Hu sheep

2022 ◽  
Author(s):  
Jie Wang ◽  
Guijiang Xu ◽  
Yu Cai ◽  
Lihong Wang ◽  
Wei Zhang
Keyword(s):  
Granulosa Cells ◽  
Cell Apoptosis ◽  
Steroid Hormone ◽  
Hormone Secretion ◽  
Hu Sheep

T-2 toxin regulates steroid hormone secretion of rat ovarian granulosa cells through cAMP-PKA pathway

2015 ◽  
Vol 232 (3) ◽  
pp. 573-579 ◽  
Author(s):  
Jing Wu ◽  
Di Tu ◽  
Li-Yun Yuan ◽  
Jin-e Yi ◽  
Yanan Tian
Keyword(s):  
Granulosa Cells ◽  
Steroid Hormone ◽  
Hormone Secretion ◽  
Ovarian Granulosa Cells ◽  
Pka Pathway

MiR-31 and miR-143 affect steroid hormone synthesis and inhibit cell apoptosis in bovine granulosa cells through FSHR

2019 ◽  
Vol 123 ◽  
pp. 45-53 ◽  
Author(s):  
Zhe Zhang ◽  
Cheng-Zhen Chen ◽  
Ming-Qiang Xu ◽  
Li-Qun Zhang ◽  
Jian-Bo Liu ◽  
...  
Keyword(s):  
Granulosa Cells ◽  
Cell Apoptosis ◽  
Steroid Hormone ◽  
Hormone Synthesis

Effect of Hyperin and Icariin on steroid hormone secretion in rat ovarian granulosa cells

2019 ◽  
Vol 495 ◽  
pp. 646-651 ◽  
Author(s):  
Xiaowei Nie ◽  
Wenjie Sheng ◽  
Daorong Hou ◽  
Qiang Liu ◽  
Ronggen Wang ◽  
...  
Keyword(s):  
Granulosa Cells ◽  
Steroid Hormone ◽  
Hormone Secretion ◽  
Ovarian Granulosa Cells

scholarly journals Gonadotropin inhibitory hormone downregulates steroid hormone secretion and genes expressions in duck granulosa cells

2021 ◽  
Vol 18 (2) ◽  
Author(s):  
Shijian Chen ◽  
Wenjun Liu ◽  
Chen Yang ◽  
Xiujin Li ◽  
Xu Shen ◽  
...  
Keyword(s):  
Granulosa Cells ◽  
Steroid Hormone ◽  
Hormone Secretion ◽  
Gonadotropin Inhibitory Hormone

scholarly journals Adverse eff ects of polymeric nanoparticle poly(ethylene glycol)- block-polylactide methyl ether (PEG-b-PLA) on steroid hormone secretion by porcine granulosa cells

2017 ◽  
Vol 51 (2) ◽  
pp. 96-104 ◽  
Author(s):  
Sona Scsukova ◽  
Mlynarcikova A. Bujnakova ◽  
A. Kiss ◽  
E. Rollerova
Keyword(s):  
Ethylene Glycol ◽  
Methyl Ether ◽  
Granulosa Cells ◽  
Steroid Hormone ◽  
Average Molecular Weight ◽  
Hormone Secretion ◽  
Poly Ethylene Glycol ◽  
Polymeric Nanoparticle ◽  
Progesterone Secretion ◽  
Poly Ethylene

AbstractObjectives. Development of nanoparticles (NPs) for biomedical applications, including medical imaging and drug delivery, is currently undergoing a dramatic expansion. Diverse effects of different type NPs relating to mammalian reproductive tissues have been demonstrated. Th e objective of this study was to explore the in vitro effects of polymeric nanoparticle poly(ethylene glycol)-blockpolylactide methyl ether (PEG-b-PLA NPs) on functional state and viability of ovarian granulosa cells (GCs), which play an important role in maintaining ovarian function and female fertility.Methods. The GCs isolated from porcine ovarian follicles were incubated with the different concentrations of PEG-b-PLA NPs (PEG average Mn=350 g/mol and PLA average Mn=1000 g/mol; 0.2-100 μg/ml) or poly(ethylene glycol) with an average molecular weight of 300 (PEG-300; 0.2- 40 mg/ml) in the presence or absence of stimulators, follicle-stimulating hormone (FSH; 1 μg/ml), androstenedione (100 nM), forskolin (10 μM) or 8Br-cAMP (100 μM), for different time periods (24, 48, 72 h). At the end of the incubation, progesterone and estradiol levels produced by GCs were measured in the culture media by radioimmunoassay. Th e viability of GCs was determined by the method using a colorimetric assay with MTT.Results. Treatment of GCs with PEG-b-PLA NPs induced a significant decrease in basal as well as FSH-stimulated progesterone secretion above the concentration of 20 and 4 μg/ml, respectively. Moreover, PEG-b-PLA NPs reduced forskolin-stimulated, but not cAMP-stimulated progesterone production by GCs. A dose-dependent inhibition of androstenedione-stimulated estradiol release by GCs was found by the action of PEG-b-PLA NPs. Incubation of GCs with PEG-300 significantly inhibited basal as well as FSH-stimulated progesterone secretion above the concentration of 40 mg/ml. PEG-b-PLA NPs and PEG-300 significantly reduced the viability of GCs at the highest tested concentrations (100 μg/ml and 40 mg/ml, respectively).Conclusions. The obtained results indicate that polymeric NPs PEG-b-PLA might induce alterations in steroid hormone production by ovarian GCs and thereby could modify reproductive functions.

Effects of recombinant goose adiponectin on steroid hormone secretion in Huoyan geese ovarian granulosa cells

2019 ◽  
Vol 205 ◽  
pp. 34-43 ◽  
Author(s):  
Bo Meng ◽  
Zhongzan Cao ◽  
Yedan Gai ◽  
Mei Liu ◽  
Ming Gao ◽  
...  
Keyword(s):  
Granulosa Cells ◽  
Steroid Hormone ◽  
Hormone Secretion ◽  
Ovarian Granulosa Cells

Effects of selected nanoparticles on in vitro steroid hormone secretion by porcine ovarian granulosa cells

2013 ◽  
Vol 41 ◽  
pp. 33-34 ◽  
Author(s):  
Sona Scsukova ◽  
Alzbeta Mlynarcikova ◽  
Kvetoslava Smolikova ◽  
Eva Rollerova
Keyword(s):  
Granulosa Cells ◽  
Steroid Hormone ◽  
Hormone Secretion ◽  
Ovarian Granulosa Cells

scholarly journals Stimulatory effect of amygdalin on the viability and steroid hormone secretion by porcine ovarian granulosa cells in vitro

2016 ◽  
Vol 05 (Special issue 1) ◽  
pp. 44-46 ◽  
Author(s):  
Marek Halenár ◽  
Eva Tušimová ◽  
Anna Nynca ◽  
Agnieszka Sadowska ◽  
Renata Ciereszko ◽  
...  
Keyword(s):  
Granulosa Cells ◽  
Steroid Hormone ◽  
Hormone Secretion ◽  
Ovarian Granulosa Cells

Effects of the FABP4 gene on steroid hormone secretion in goose ovarian granulosa cells

2020 ◽  
pp. 1-11
Author(s):  
R. Fan ◽  
Z. Cao ◽  
M. Chen ◽  
H. Wang ◽  
M. Liu ◽  
...  
Keyword(s):  
Granulosa Cells ◽  
Steroid Hormone ◽  
Hormone Secretion ◽  
Ovarian Granulosa Cells
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