Non-motor effects of subthalamic nucleus stimulation in Parkinson patients

2022 ◽  
Author(s):  
Francesco Sammartino ◽  
Rachel Marsh ◽  
Ali Rezai ◽  
Vibhor Krishna
Keyword(s):  
Subthalamic Nucleus ◽  
Subthalamic Nucleus Stimulation ◽  
Motor Effects

Neurophysiological Correlates of Motor and Working Memory Performance following Subthalamic Nucleus Stimulation

2013 ◽  
Vol 25 (1) ◽  
pp. 37-48 ◽  
Author(s):  
Katherine Selzler ◽  
Michelle Burack ◽  
Ryan Bender ◽  
Mark Mapstone
Keyword(s):  
Working Memory ◽  
Visual Working Memory ◽  
Subthalamic Nucleus ◽  
Motor Function ◽  
Memory Performance ◽  
Memory Task ◽  
Motor Disability ◽  
Subthalamic Nucleus Stimulation ◽  
Motor Effects ◽  
Stn Dbs

Subthalamic nucleus (STN) deep brain stimulation (DBS) has become an accepted treatment for the motor manifestations of Parkinson disease (PD). The beneficial motor effects of STN DBS are likely due to modulation of BG output to frontal cortical regions associated with motor control, but the underlying neurophysiology of STN DBS effects, especially at the level of the cortex, is not well understood. In this study, we examined the effects of STN DBS on motor disability and visual working memory, a cognitive process supported by pFC. We tested 10 PD participants off medications, ON and OFF stimulation, along with 20 normal controls on a visual working memory task while simultaneously recording cortical EEG. In the OFF state, PD patients had poor motor function, were slower and less accurate in performing the working memory task, and had greater amplitudes and shorter latencies of the N200 ERP response. DBS improved clinical motor function, reduced N200 amplitudes, and increased N200 latencies but had little effect on working memory performance. We conclude that STN DBS normalizes neurophysiological activity in fronto striatal circuits and this may independently affect motor and cognitive function.

Pedunculopontine nucleus evoked potentials from subthalamic nucleus stimulation in Parkinson's disease

2013 ◽  
Vol 250 ◽  
pp. 221-227 ◽  
Author(s):  
Bogdan Neagu ◽  
Eric Tsang ◽  
Filomena Mazzella ◽  
Clement Hamani ◽  
Elena Moro ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Evoked Potentials ◽  
Subthalamic Nucleus ◽  
Pedunculopontine Nucleus ◽  
Subthalamic Nucleus Stimulation

Complex repetitive behavior: Punding after bilateral subthalamic nucleus stimulation in Parkinson's disease

2010 ◽  
Vol 16 (6) ◽  
pp. 376-380 ◽  
Author(s):  
Stefano Pallanti ◽  
Silvia Bernardi ◽  
Laura Maria Raglione ◽  
Paolo Marini ◽  
Franco Ammannati ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Subthalamic Nucleus ◽  
Repetitive Behavior ◽  
Subthalamic Nucleus Stimulation

scholarly journals Effects of Subthalamic Nucleus Stimulation on Emotional Prosody Comprehension in Parkinson's Disease

PLoS ONE ◽  
2011 ◽  
Vol 6 (4) ◽  
pp. e19140 ◽  
Author(s):  
Carolin Brück ◽  
Dirk Wildgruber ◽  
Benjamin Kreifelts ◽  
Rejko Krüger ◽  
Tobias Wächter
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Subthalamic Nucleus ◽  
Emotional Prosody ◽  
Subthalamic Nucleus Stimulation
Sign in / Sign up

Export Citation Format

Share Document