Mid-term oncologic outcome of a novel approach for locally advanced colon cancer with neoadjuvant chemotherapy and surgery

2016 ◽  
Vol 19 (3) ◽  
pp. 379-385 ◽  
Author(s):  
J. Arredondo ◽  
J. Baixauli ◽  
C. Pastor ◽  
A. Chopitea ◽  
J. J. Sola ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Locally Advanced ◽  
Oncologic Outcome ◽  
Advanced Colon Cancer ◽  
Novel Approach

Neoadjuvant chemotherapy in locally advanced colon cancer: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Rathin Gosavi ◽  
Clemente Chia ◽  
Michael Michael ◽  
Alexander G. Heriot ◽  
Satish K. Warrier ◽  
...  
Keyword(s):  
Systematic Review ◽  
Colon Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Meta Analysis ◽  
Locally Advanced ◽  
Advanced Colon Cancer

scholarly journals Tumor regression after neoadjuvant chemotherapy in locally advanced colon cancer

2015 ◽  
Vol 5 (3) ◽  
pp. 33
Author(s):  
A. O. Rasulov ◽  
V. M. Kulushev ◽  
V. S. Ananiev ◽  
M. Yu. Fedyanin ◽  
N. A. Kozlov
Keyword(s):  
Colon Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Tumor Regression ◽  
Locally Advanced ◽  
Advanced Colon Cancer

Neoadjuvant chemotherapy in locally advanced colon cancer: a systematic review

2020 ◽  
Vol 24 (10) ◽  
pp. 1001-1015
Author(s):  
J. Arredondo ◽  
E. Pastor ◽  
V. Simó ◽  
M. Beltrán ◽  
C. Castañón ◽  
...  
Keyword(s):  
Systematic Review ◽  
Colon Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Locally Advanced ◽  
Advanced Colon Cancer

Complete Pathologic Response After Neoadjuvant Chemotherapy in Locally Advanced Colon Cancer

2020 ◽  
Vol 98 (3) ◽  
pp. 168-170
Author(s):  
Jorge Arredondo ◽  
Vicente Simó ◽  
Carmen Castañón ◽  
María José Suárez ◽  
María Concepción Álvarez
Keyword(s):  
Colon Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Locally Advanced ◽  
Pathologic Response ◽  
Complete Pathologic Response ◽  
Advanced Colon Cancer

scholarly journals The Role of Neoadjuvant Chemotherapy in Locally Advanced Colon Cancer

2021 ◽  
Vol Volume 13 ◽  
pp. 2567-2579
Author(s):  
Amy Body ◽  
Hans Prenen ◽  
Sarah Latham ◽  
Marissa Lam ◽  
Samuel Tipping-Smith ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Locally Advanced ◽  
Advanced Colon Cancer

A marker-driven phase II trial of neoadjuvant chemotherapy in locally advanced colon cancer.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. 3621-3621
Author(s):  
Anders Kristian Moeller Jakobsen ◽  
Fahimeh Andersen ◽  
Anders Fischer ◽  
Lars Henrik Jensen ◽  
Jens Christian Riis Joergensen ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Neoadjuvant Chemotherapy ◽  
Phase Ii ◽  
Phase Ii Trial ◽  
Locally Advanced ◽  
Advanced Colon Cancer

Concomitant Adjacent Organ Resection in Locally Advanced Colon Cancer

2009 ◽  
Vol 25 (2) ◽  
pp. 94 ◽  
Author(s):  
Sung Wook Cho ◽  
Ryung-Ah Lee ◽  
Soon Sup Chung ◽  
Kwang Ho Kim
Keyword(s):  
Colon Cancer ◽  
Locally Advanced ◽  
Adjacent Organ ◽  
Advanced Colon Cancer

scholarly journals Differences in effectiveness and use of laparoscopic surgery in locally advanced colon cancer patients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
M. Schootman ◽  
Matthew Mutch ◽  
T. Loux ◽  
J. M. Eberth ◽  
N. O. Davidson
Keyword(s):  
Colon Cancer ◽  
Length Of Stay ◽  
Cancer Patients ◽  
Postoperative Ileus ◽  
Locally Advanced ◽  
Composite Outcome ◽  
Improvement Program ◽  
Advanced Colon Cancer ◽  
Outcome Score ◽  
T4 Colon Cancer

AbstractPatients with locally advanced colon cancer have worse outcomes. Guidelines of various organizations are conflicting about the use of laparoscopic colectomy (LC) in locally advanced colon cancer. We determined whether patient outcomes of LC and open colectomy (OC) for locally advanced (T4) colon cancer are comparable in all colon cancer patients, T4a versus T4b patients, obese versus non-obese patients, and tumors located in the ascending, descending, and transverse colon. We used data from the 2013–2015 American College of Surgeons’ National Surgical Quality Improvement Program. Patients were diagnosed with nonmetastatic pT4 colon cancer, with or without obstruction, and underwent LC (n = 563) or OC (n = 807). We used a composite outcome score (mortality, readmission, re-operation, wound infection, bleeding transfusion, and prolonged postoperative ileus); length of stay; and length of operation. Patients undergoing LC exhibited a composite outcome score that was 9.5% lower (95% CI − 15.4; − 3.5) versus those undergoing OC. LC patients experienced a 11.3% reduction in postoperative ileus (95% CI − 16.0; − 6.5) and an average of 2 days shorter length of stay (95% CI − 2.9; − 1.0). Patients undergoing LC were in the operating room an average of 13.5 min longer (95% CI 1.5; 25.6). We found no evidence for treatment heterogeneity across subgroups (p > 0.05). Patients with locally advanced colon cancer who receive LC had better overall outcomes and shorter lengths of stay compared with OC patients. LC was equally effective in obese/nonobese patients, in T4a/T4b patients, and regardless of the location of the tumor.

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