Occasional Staining for p63 in Malignant Vascular Tumors: A Potential Diagnostic Pitfall

2011 ◽  
Vol 18 (1) ◽  
pp. 97-100 ◽  
Author(s):  
Michael E. Kallen ◽  
Flavia G. Nunes Rosado ◽  
Adriana L. Gonzalez ◽  
Melinda E. Sanders ◽  
Justin M. M. Cates
2020 ◽  
Vol 49 ◽  
pp. 151589
Author(s):  
Hee Eun Lee ◽  
Michael S. Torbenson ◽  
Tsung-Teh Wu ◽  
Vishal S. Chandan

BMJ ◽  
1974 ◽  
Vol 1 (5901) ◽  
pp. 248-248
Author(s):  
G. A. Jackson ◽  
P. M. Fea
Keyword(s):  

2021 ◽  
pp. 004947552110206
Author(s):  
Prasad Dange ◽  
Ankesh Gupta ◽  
Richa Juneja ◽  
Renu Saxena

Long-standing moderate to marked splenomegaly suggests several differential diagnoses, both haematological and infectious, particularly leishmaniasis and malaria in endemic areas. Non-infectious causes may be missed in these regions, especially if pitfalls of serological testing are not considered. Careful patient evaluation is necessary to arrive at the correct diagnosis. We report a case of a young male whose hereditary spherocytosis was initially missed because of RK-39 positivity, splenomegaly and the fact that he hailed from an endemic region.


2021 ◽  
Vol 13 (3) ◽  
pp. 347-356
Author(s):  
Aoife Naughton ◽  
Ariel Yuhan Ong ◽  
Goran Darius Hildebrand

Infantile hemangiomas are common benign vascular tumors but are rarely found in an intracranial location. Our literature review identified 41 reported cases. There is no general consensus on management of these rare lesions and until recently, treatment was limited to surgery or pharmacological management with steroids or interferon. Although beta-blockers have been widely prescribed in the treatment of cutaneous infantile hemangiomas since 2008, their use in the treatment of intracranial infantile hemangiomas has been minimal. We present a case of infantile hemangioma affecting the right orbit, associated with intracranial extension, causing intermittent right facial nerve palsy. The patient achieved an excellent outcome following combined treatment with oral propranolol and topical timolol maleate 0.5%, with complete regression of the lesion by 4 months. We conclude that beta-blockers are a safe and effective treatment of intracranial infantile hemangiomas and can be employed as first-line management of these lesions.


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