The effectiveness of simultaneous oncoplastic breast surgery in patients with locally advanced breast cancer

Breast Cancer ◽  
2015 ◽  
Vol 23 (3) ◽  
pp. 463-470 ◽  
Author(s):  
Mustafa Emiroglu ◽  
Ismail Sert ◽  
Cem Karaali ◽  
Süleyman Ozkan Aksoy ◽  
Levent Ugurlu ◽  
...  
2002 ◽  
Vol 91 (3) ◽  
pp. 222-226 ◽  
Author(s):  
K. Sandelin ◽  
J. P. Apffelstaedt ◽  
H. Abdullah ◽  
E. M. Murray ◽  
E. U. Ajuluchuku

Breast Surgery International (BSI) was formed in 1999 as an integrated society within the International Surgical Society ISS/SIC. One goal is to promote breast surgery world wide and focus on the situation in the developing countries. An edited summary of a symposium on locally advanced breast cancer (LABC) and the current situation in two African countries and in Malaysia is reported. Diagnosis, management and treatment options differ from recommendations that prevail due to lack of resources, lack of access to facilities and cultural and socioeconomic barriers. Younger age at onset, more men are affected and locally advanced breast cancer dominates the clinical panorama. A rational treatment plan for LABC should have chemotherapy, surgery, radiotherapy and hormonal therapy as armaments. A unique opportunity exists for international interchange within a professional organization such as BSI, for providing training opportunities, for clinical and experimental studies of the world's most common female malignancy.


2019 ◽  
Vol 6 (2) ◽  
pp. 459
Author(s):  
Alaa A. El Sisi ◽  
Mahmoud G. Hagag ◽  
Mohammed G. Hegazi

Background: Locally advanced breast cancer represents 20%-25% of breast cancer patients at diagnosis. The aim of this prospective study was to assess the feasibility and the oncologic outcome in the treatment of patients of locally advanced breast cancer that had been downstaged by neoadjuvant chemotherapy to the extent that makes them eligible for conservative breast surgery.Methods: This prospective study was done on 50 female patients who were diagnosed with locally advanced breast cancer and received neoadjuvant chemotherapy to downstage cancer making it eligible for conservation, managed and treated at El Menoufia University Hospital and Tanta Cancer Center from March 2017 to March 2018 after applying inclusion and exclusion criteria. The collected data were organized, tabulated and statistically analyzed using SPSS software.Results: Significant difference between pre and post-chemotherapy tumor size in patients with locally advanced breast cancer. Conservative breast surgery with intraoperative frozen section assured free margins in all of them with acceptable cosmetic outcome. No local recurrence recorded after one year of follow up.Conclusions: In the present study, it was observed that conventional neoadjuvant chemotherapy is effective in downgrading the tumor size and axillary lymph nodes in patients with locally advanced breast cancer. Breast conservation after neoadjuvant chemotherapy is safe in terms of local recurrence.


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